Exposure to particulate silica (most crystalline polymorphs) causes a persistent inflammation
sustained by the release of oxidants in the alveolar space. Reactive oxygen species (ROS) …

Inhalation of the crystalline form of silica is associated with a variety of pathologies, from
acute lung inflammation to silicosis, in addition to autoimmune disorders and cancer. Basic …

Reactive oxygen species (ROS) are products of normal cellular metabolism and are known
to act as second messengers. Under physiological conditions, ROS participate in …

Further research on the molecular mechanisms involved in the inflammatory processes
important for progression to fibrotic diseases is needed for the development of effective …

The toxic effects of air pollution are widely documented. In recent years, however, there has
been an increasing interest in the study of the health effects of particulate matter (PM), a …

Hydrogen peroxide increases extracellular matrix mRNA through TGF-β in human
mesangial cells. Background Reactive oxygen species (ROS) are excessively produced in …

Occupational exposure to crystalline silica has been linked to pulmonary fibrosis and lung
cancer. Surface properties of crystalline silica are critical to the production of oxidant …

In this study we identified the involvement of reactive oxygen species (ROS) in signaling and
biological effects of the angiopoietin‐1 (Ang‐1)/tie‐2 receptor pathway. Exposure of human …

Exposure to particles in industry and mining and from accidental anthropogenic sources
constitutes an ongoing threat. Most recently nanoparticles arising from advances in …

Coal dust inhalation induces oxidative damage and inflammatory infiltration on lung
parenchyma. Thus, the aim of this study was to determine whether N-acetylcysteine (NAC) …