The history of Alzheimer's disease (AD) started in 1907, but we needed to wait until the end
of the century to identify the components of pathological hallmarks and genetic subtypes and …

Mechanisms of epigenetic regulation, including DNA methylation, chromatin remodeling,
and histone post-translational modifications, are involved in multiple aspects of neuronal …

Alzheimer's disease (AD) is characterized by non-linear, genetic-driven pathophysiological
dynamics with high heterogeneity in biological alterations and disease spatial-temporal …

The dominant hypothesis of Alzheimer's disease (AD) aetiology, the neuropathological
guidelines for diagnosing AD and the majority of high-profile therapeutic efforts, in both …

Recent studies have suggested the role of an infectious component in the pathogenesis of
Alzheimer's disease (AD). In light of this, research has focused on some bacteria constituting …

Cognitive impairment in Alzheimer's disease (AD) is associated with dysregulation of the
RNA and protein expression profiles in the brain. Recent studies have highlighted the …

Alzheimer's disease (AD) is a chronic, progressive and prevalent neurodegenerative
disease characterized by the loss of higher cognitive functions and an associated loss of …

Cognitive impairment (CI) refers to the dysfunction of memory, language, visual space,
execution, calculation, understanding, and judgment in one or more aspects. With global …

So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

During the twentieth century, genes were considered the controlling force of life processes,
and the transfer of DNA the definitive explanation for biological heredity. Such views shaped …