The past, present, and future of antibiotics
MA Cook, GD Wright - Science Translational Medicine, 2022 - science.org
Antibiotics have transformed modern medicine. They are essential for treating infectious
diseases and enable vital therapies and procedures. However, despite this success, their …
diseases and enable vital therapies and procedures. However, despite this success, their …
[HTML][HTML] Shaping the future of probiotics and prebiotics
M Cunningham, MA Azcarate-Peril, A Barnard… - Trends in …, 2021 - cell.com
Recent and ongoing developments in microbiome science are enabling new frontiers of
research for probiotics and prebiotics. Novel types, mechanisms, and applications currently …
research for probiotics and prebiotics. Novel types, mechanisms, and applications currently …
Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
[HTML][HTML] Progress in alternative strategies to combat antimicrobial resistance: Focus on antibiotics
Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR),
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
continues to evolve and spread beyond all boundaries. As a result, infectious diseases have …
Antimicrobial resistance in ESKAPE pathogens
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …
[HTML][HTML] A bottom-up view of antimicrobial resistance transmission in developing countries
OO Ikhimiukor, EE Odih, P Donado-Godoy… - Nature …, 2022 - nature.com
Antimicrobial resistance (AMR) is tracked most closely in clinical settings and high-income
countries. However, resistant organisms thrive globally and are transmitted to and from …
countries. However, resistant organisms thrive globally and are transmitted to and from …
Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials
S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl… - EMBO …, 2023 - embopress.org
Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …
[HTML][HTML] A new era of antibiotics: the clinical potential of antimicrobial peptides
Antimicrobial resistance is a multifaceted crisis, imposing a serious threat to global health.
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …
The traditional antibiotic pipeline has been exhausted, prompting research into alternate …
[HTML][HTML] Towards the sustainable discovery and development of new antibiotics
An ever-increasing demand for novel antimicrobials to treat life-threatening infections
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
caused by the global spread of multidrug-resistant bacterial pathogens stands in stark …
Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections
Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …
effector immune defense molecules in multicellular organisms. AMPs exert their …