Within the life cycle of a living organism, another life cycle exists for the selfish genome
inhabitants, which are called transposable elements (TEs). These mobile sequences invade …

Genetic changes causing brain size expansion in human evolution have remained elusive.
Notch signaling is essential for radial glia stem cell proliferation and is a determinant of …

INTRODUCTION Understanding the genetic differences that make us human is a long-
standing endeavor that requires the comprehensive discovery and comparison of all forms …

ABSTRACT Long interspersed element‐1 (LINE‐1 or L1) is a transposable element with the
ability to self‐mobilize throughout the human genome. The L1 elements found in the human …

How gene expression is controlled to preserve human T cell quiescence is poorly
understood. Here we show that non-canonical splicing variants containing long interspersed …

Unique aspects of human behavior are often attributed to differences in the relative size and
organization of the human brain: these structural aspects originate during early …

Humans may share more genomic commonalities with other species than previously
thought. According to current estimates,~ 5% of the human genome is functionally …

Summary Long interspersed element-1 (LINE-1 or L1) comprises 17% of the human
genome, continuously generates genetic variations, and causes disease in certain cases …

Transposable elements (TEs) through evolutionary exaptation have become an integral part
of the human genome, offering ample regulatory sequences and shaping chromatin 3D …

Membranous organelles allow sub‐compartmentalization of biological processes. However,
additional subcellular structures create dynamic reaction spaces without the need for …