Recent advances in bioprocessing application of membrane chromatography
Compared to traditional chromatography using resins in packed-bed columns, membrane
chromatography is a relatively new and immature bioseparation technology based on the …
chromatography is a relatively new and immature bioseparation technology based on the …
The transition from resin chromatography to membrane adsorbers for protein separations at industrial scale
Y Qu, I Bekard, B Hunt, J Black, L Fabri… - Separation & …, 2024 - Taylor & Francis
Membrane adsorbers (MA) are emerging as alternative unit operations in high-value protein
separation due to their many benefits, including short residence times, low pressure drop …
separation due to their many benefits, including short residence times, low pressure drop …
Towards next generation high throughput ion exchange membranes for downstream bioprocessing: A review
Membrane chromatography is recognised as a potential solution to streamline downstream
processing for protein purification, where ion exchange membrane chromatography (IEMC) …
processing for protein purification, where ion exchange membrane chromatography (IEMC) …
An overview of mechanistic modeling of liquid chromatography
LK Shekhawat, AS Rathore - Preparative biochemistry and …, 2019 - Taylor & Francis
Liquid chromatography is considered to be the bottleneck for purification of therapeutic
proteins. Development and optimization of chromatography process is a cumbersome …
proteins. Development and optimization of chromatography process is a cumbersome …
[HTML][HTML] Why device design is crucial for membrane adsorbers
F Hagemann, D Wypysek, K Baitalow… - Journal of …, 2022 - Elsevier
In preparative chromatography, a uniform flow distribution through the chromatography
device is essential to get an effective ligand utilization and a breakthrough curve that is as …
device is essential to get an effective ligand utilization and a breakthrough curve that is as …
Membrane processes for whey proteins separation and purification. A review
R Aguero, E Bringas, MF San Roman… - Current Organic …, 2017 - ingentaconnect.com
Background: Whey is a valuable by-product obtained from cheese manufacture and
employed as a source of proteins that present remarkable potential in food or …
employed as a source of proteins that present remarkable potential in food or …
Convection rather than diffusion for fast efficient mRNA vaccine purification
R Banik, TG Neuman, Z Hao, M Al Sharabati… - Separation and …, 2025 - Elsevier
In the rush to produce mRNA vaccines and ensure integrity and purity, capital-intensive
purification steps were used, typically involving slow diffusion-driven, inefficient, and costly …
purification steps were used, typically involving slow diffusion-driven, inefficient, and costly …
A z2 laterally-fed membrane chromatography device for fast high-resolution purification of biopharmaceuticals
We examine the use of az 2 flow distribution and collection feature for enhancing the
separation efficiency of a laterally-fed membrane chromatography (or LFMC) device. The …
separation efficiency of a laterally-fed membrane chromatography (or LFMC) device. The …
Study of the adsorption of proteins on stainless steel surfaces using QCM-D
N Chandrasekaran, S Dimartino, CJ Fee - Chemical Engineering Research …, 2013 - Elsevier
Stainless steel is widely used in a number of industries, ranging from food and dairy to
pharmaceuticals. However, fouling associated with protein adsorption constitutes a main …
pharmaceuticals. However, fouling associated with protein adsorption constitutes a main …
Predicting steroid hormone removal in a thin activated carbon layer coupled with ultrafiltration
Ultrafiltration coupled with a thin polymer-based activated carbon (PBSAC) layer promises to
tackle the challenge of estrogenic micropollutants in water. The proposed drinking water …
tackle the challenge of estrogenic micropollutants in water. The proposed drinking water …