Antimicrobial resistance is now considered a major global challenge; compromising medical
advancements and our ability to treat infectious disease. Increased antimicrobial resistance …

Despite extensive global efforts in the fight against killer infectious diseases, they still cause
one in four deaths worldwide and are important causes of long-term functional disability …

To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism
(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene …

Infectious diseases continue to threaten human and animal health and welfare globally,
impacting millions of lives and causing substantial economic loss. The use of antibacterials …

Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites
of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs …

Staphylococcus aureus infection is a common cause of mastitis, reducing milk yield,
affecting animal welfare and causing huge economic losses within the dairy industry. In …

Exposure to humidifier disinfectants was identified in 2011 as the potential cause of an
outbreak of lung disease in Korea. It is estimated that over 8 million people have been …

Objectives The treatment of skin infections caused by Staphylococcus aureus is limited by
acquired antibiotic resistance and poor drug delivery into pathogen and host cells. Here, we …

Background The therapy of visceral leishmaniasis (VL) is limited by resistance, toxicity and
decreased bioavailability of the existing drugs coupled with dramatic increase in HIV-co …

Topical wound infections create the ideal conditions for microbial colonization and growth in
terms of moisture, temperature, and nutrients. When they are not protected, numerous types …