Metallo-drugs in cancer therapy: Past, present and future

RL Lucaciu, AC Hangan, B Sevastre, LS Oprean - Molecules, 2022 - mdpi.com
Cancer treatments which include conventional chemotherapy have not proven very
successful in curing human malignancies. The failures of these treatment modalities include …

Riding the metal wave: A review of the latest developments in metal-based anticancer agents

S Abdolmaleki, A Aliabadi, S Khaksar - Coordination Chemistry Reviews, 2024 - Elsevier
Metal-based complexes have demonstrated significant anticancer effects and have emerged
as candidates with great potential for cancer therapy. These agents are effective in a variety …

Applications of metal complexes in analytical chemistry: A review article

RH Elattar, SF El-Malla, AH Kamal… - Coordination Chemistry …, 2024 - Elsevier
Metal complexes are commonly utilized substances in the field of analytical chemistry. They
can be synthesized to possess specific molecular geometries, thereby enabling the …

Metal Complexes in cancer treatment: Journey so far

A Kumar Singh, A Kumar, H Singh… - Chemistry & …, 2023 - Wiley Online Library
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …

Innovation of Fe (III), Ni (II), and Pd (II) complexes derived from benzothiazole imidazolidin‐4‐ol ligand: Geometrical elucidation, theoretical calculation, and …

AM Abu‐Dief, MA Said, O Elhady… - Applied …, 2023 - Wiley Online Library
The synthesis of a simple, highly tunable, and effective BSI ligand, 2‐(benzothiazol‐2‐
ylimino)‐2, 3‐dihydro‐1H‐imidazol‐4‐ol, was presented. Three new coordinating …

Cytotoxicity and mechanism of action of metal complexes: An overview

S Abdolmaleki, S Khaksar, A Aliabadi, A Panjehpour… - Toxicology, 2023 - Elsevier
After the discovery of cisplatin, many metal compounds were investigated for the therapy of
diseases, especially cancer. The high therapeutic potential of metal-based compounds is …

[HTML][HTML] Biomimetic theranostic nanoparticles for effective anticancer therapy and MRI imaging

MJ Bigaj-Józefowska, E Coy, K Załęski… - … of Photochemistry and …, 2023 - Elsevier
Cancer remains a leading cause of mortality worldwide, necessitating the development of
innovative therapeutic approaches. Nanoparticle-based drug delivery systems have …

Oxidation states in metallocenes: A key mechanistic component in cancer alleviation

R Das, DR Chatterjee, A Shard - Coordination Chemistry Reviews, 2024 - Elsevier
Metal complexes are widely employed in cancer treatment. The several tuning variables
provide peerless possibilities for drug development strategies. This results in a diverse …

Recent Advances in Bioconjugated Transition Metal Complexes for Cancer Therapy

E Bortolamiol, F Visentin, T Scattolin - Applied Sciences, 2023 - mdpi.com
The introduction of biologically relevant organic moieties in the coordination sphere of
transition metal complexes has recently become a well-established strategy to increase the …

Effect of the extra-nuclear cation on the cytotoxicity and mechanism of action of pyridine-2, 6-dicarboxylate Ga (III) complexes

S Khaksar, A Aliabadi, A Panjehpour, S Abdolmaleki - Toxicology, 2023 - Elsevier
Abstract Two Ga (III) complexes (C1) and (C2) were prepared by the one-pot reaction of
pyridine-2, 6-dicarboxylic acid and aminopyridine derivatives with gallium (III) nitrate …