Targeting the neural stem cells in subventricular zone for the treatment of glioblastoma: an update from preclinical evidence to clinical interventions

S Li, L Dong, Z Pan, G Yang - Stem Cell Research & Therapy, 2023 - Springer
Background Glioblastoma is one of the most common and aggressive adult brain tumors.
The conventional treatment strategy, surgery combined with chemoradiotherapy, did not …

Prognostic analysis and nomogram construction for older patients with IDH-wild-type glioblastoma

W Cao, L Xiong, L Meng, Z Li, Z Hu, H Lei, J Wu… - Heliyon, 2023 - cell.com
As many countries face an ageing population, the number of older patients with
glioblastoma (GB) is increasing. Thus, there is an urgent need for prognostic models to aid …

Immunohistochemical detection of neural stem cells and glioblastoma stem cells in the subventricular zone of glioblastoma patients

VVV Hira, RJ Molenaar, B Breznik… - … of Histochemistry & …, 2021 - journals.sagepub.com
Glioblastoma usually recurs after therapy consisting of surgery, radiotherapy, and
chemotherapy. Recurrence is at least partly caused by glioblastoma stem cells (GSCs) that …

Defining subventricular zone involvement to predict the survival of patients in isocitrate dehydrogenase-wild type glioblastoma: validation in a prospective registry

JE Kim, JE Park, SY Park, YH Kim, CK Hong, JH Kim… - European …, 2023 - Springer
Objectives The prognostic value of subventricular zone distance (SVD) is unclear because
of different definitions and lack of evaluation of clinical survival models. The aim of this study …

The imaging features and prognosis of gliomas involving the subventricular zone: an MRI study

K Zhao, R Liu, Z Li, M Liu, Y Zhao, Z Xue, W Wu… - Clinical Neurology and …, 2022 - Elsevier
Rationale and objectives As the largest concentrated region of neural stem cells in the adult
brain, the subventricular zone (SVZ) is considered to have a close relationship with the …

Quantitative Assessment of Tumor Contact with Neurogenic Zones and Its Effects on Survival: Insights beyond Traditional Predictors

K Jung, J Kempter, G Prokop, T Herrmann… - Cancers, 2024 - mdpi.com
Simple Summary The exact cellular origin of glioblastoma (GBM) remains uncertain, with
prevalent theories suggesting emergence from transformed endogenous stem cells. These …

Voxelwise Prediction of Recurrent High-Grade Glioma via Proximity Estimation–Coupled Multidimensional Support Vector Machine

Y Lao, D Ruan, A Vassantachart, Z Fan… - International Journal of …, 2022 - Elsevier
Purpose To provide early and localized glioblastoma (GBM) recurrence prediction, we
introduce a novel postsurgery multiparametric magnetic resonance–based support vector …

[HTML][HTML] FGF14-AS2 accelerates tumorigenesis in glioma by forming a feedback loop with miR-320a/E2F1 axis

P Zhang, X Gu, N Zhang, L Liu, X Dong, H Li… - Journal of …, 2021 - ncbi.nlm.nih.gov
Glioma is the most common primary tumour in the central nervous system in adults, and at
present, there is no effective treatment to cure this malignancy. Long noncoding RNAs …

CC motif chemokine ligand 2/CC receptor 2 is associated with glioma recurrence and poor survival

Q Yang, J Zhang, X Zhang, L Miao… - Experimental and …, 2021 - spandidos-publications.com
Several studies have explored the mechanisms of C‑C motif chemokine ligand (CCL) 2/CC
receptor (R) 2 function in tumorigenesis and inflammation. However, little is known about the …

Relationship between molecular characteristics of glioblastoma multiforme and the subventricular zone

M Ashraf, M Abdelsadg, A Grivas - British Journal of Neurosurgery, 2022 - Taylor & Francis
Objective This study aims to assess the relationship between the molecular characteristics of
glioblastoma multiforme (GBM) and the subventricular zone (SVZ) Material and Methods …