The human gut microbiome is a diverse and complex ecosystem that plays a critical role in
health and disease. The composition of the gut microbiome has been well studied across all …

The threat of novel influenza infections has sparked research efforts to develop subunit
vaccines that can induce a more broadly protective immunity by targeting selected regions of …

Bovine respiratory disease (BRD) is a significant health issue in the North American feedlot
industry, causing substantial financial losses due to morbidity and mortality. A lack of …

Bacillus subtilis is a widely distributed aerobic Gram-positive species of bacteria. As a tool in
the lab, it has the advantages of nonpathogenicity and limited likelihood of becoming drug …

Vaccines have been one of the most powerful weapons to defend against infectious
diseases for a long time now. Subunit vaccines are of increasing importance because of …

Chicken NK-lysin peptide 2 (cNK-2) is a natural lytic peptide with direct cytotoxicity against
many apicomplexan parasites including Eimeria. Developing an effective oral delivery …

Oral drug delivery has attracted substantial attention due to its advantages over other
administration routes. Bacillus spores, as oral probiotic agents, are applied widely. In this …

The development of efficient mucosal vaccines is strongly dependent on the use of
appropriate vectors. Various biological systems or synthetic nanoparticles have been …

Display systems that present biologically active molecules on the surface of microorganisms
have become increasingly used to address environmental and biomedical issues (1–3) …

Abstract Background Clonorchiasis caused by Clonorchis sinensis has become increasingly
prevalent in recent years. Effective prevention strategies are urgently needed to control this …