[HTML][HTML] Silybin and the liver: from basic research to clinical practice

C Loguercio, D Festi - World journal of gastroenterology: WJG, 2011 - ncbi.nlm.nih.gov
Herbal products are increasingly used, mainly in chronic liver disease. Extracts of milk
thistle, Silymarin and silybin, are the most prescribed natural compounds, with different …

Multitargeted therapy of cancer by silymarin

K Ramasamy, R Agarwal - Cancer letters, 2008 - Elsevier
Silymarin, a flavonolignan from milk thistle (Silybum marianum) plant, is used for the
protection against various liver conditions in both clinical settings and experimental models …

Survivin: a new target for anti-cancer therapy

BM Ryan, N O'Donovan, MJ Duffy - Cancer treatment reviews, 2009 - Elsevier
Survivin is one of the most cancer-specific proteins identified to date, being upregulated in
almost all human tumors. Biologically, survivin has been shown to inhibit apoptosis …

Silymarin in the prevention and treatment of liver diseases and primary liver cancer

J Fehér, G Lengyel - Current pharmaceutical biotechnology, 2012 - ingentaconnect.com
In chronic liver diseases caused by oxidative stress (alcoholic and non-alcoholic fatty liver
diseases, drug-and chemical-induced hepatic toxicity), the antioxidant medicines such as …

Silver Nanoparticles Synthesized Using Carica papaya Leaf Extract (AgNPs-PLE) Causes Cell Cycle Arrest and Apoptosis in Human Prostate (DU145) Cancer Cells

SP Singh, A Mishra, RK Shyanti, RP Singh… - … Trace Element Research, 2021 - Springer
Abstract Treatment of cancer has been limited by the poor efficacy and toxicity profiles of
available drugs. There is a growing demand to develop alternative approaches to combat …

Chemopreventive effects of natural dietary compounds on cancer development

MH Pan, CT Ho - Chemical Society Reviews, 2008 - pubs.rsc.org
Chemoprevention, a relatively new and promising strategy to prevent cancer, is defined as
the use of natural dietary compounds and/or synthetic substances to block, inhibit, reverse …

Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer

G Deep, R Agarwal - Cancer and Metastasis Reviews, 2010 - Springer
Cancer is a major health problem around the world. Research efforts in the last few decades
have been successful in providing better and effective treatments against both early stage …

Lifestyle as risk factor for cancer: Evidence from human studies

N Khan, F Afaq, H Mukhtar - Cancer letters, 2010 - Elsevier
It is increasingly appreciated that the chances of developing cancer are significantly affected
by the choice of our lifestyle. There are several uncontrollable risk factors which account for …

A study of high‐dose oral silybin‐phytosome followed by prostatectomy in patients with localized prostate cancer

TW Flaig, M Glodé, D Gustafson, A van Bokhoven… - The …, 2010 - Wiley Online Library
BACKGROUND Silibinin is a polyphenolic flavonolignan derived from milk thistle (Silybum
marianium) with anti‐oxidant properties. The purpose of the current trial was to determine …

Influence of the bioactive diet components on the gene expression regulation

J Mierziak, K Kostyn, A Boba, M Czemplik, A Kulma… - Nutrients, 2021 - mdpi.com
Diet bioactive components, in the concept of nutrigenetics and nutrigenomics, consist of food
constituents, which can transfer information from the external environment and influence …