NSAIDs/nitazoxanide/azithromycin repurposed for COVID-19: potential mitigation of the cytokine storm interleukin-6 amplifier via immunomodulatory effects
MT Kelleni - Expert Review of Anti-infective Therapy, 2022 - Taylor & Francis
Introduction Mediators of immunity and inflammation are playing a crucial role in COVID-19
pathogenesis and complications as demonstrated by several genetic and clinical studies …
pathogenesis and complications as demonstrated by several genetic and clinical studies …
New insights on tramadol and immunomodulation
Abstract Purpose of Review Opioids are administered to cancer patients although concerns
have been raised that they may promote tumour growth or metastasis owing to their ability to …
have been raised that they may promote tumour growth or metastasis owing to their ability to …
The harmful effects of acute PM2.5 exposure to the heart and a novel preventive and therapeutic function of CEOs
L Dong, W Sun, F Li, M Shi, X Meng, C Wang… - Scientific Reports, 2019 - nature.com
Epidemiological researches have demonstrated the relationship between PM2. 5 exposure
and increased morbidity and mortality of cardiovascular injury. However, no effective …
and increased morbidity and mortality of cardiovascular injury. However, no effective …
Incidence of alveolar osteitis after mandibular third molar surgery. Can inflammatory cytokines be identified locally?
H Øyri, JL Jensen, P Barkvoll… - Acta Odontologica …, 2021 - Taylor & Francis
Objectives The aims of the present study were to evaluate the relative incidence of alveolar
osteitis (AO) after mandibular third molar surgery, post-operative findings and local …
osteitis (AO) after mandibular third molar surgery, post-operative findings and local …
Further Evidence of Possible Therapeutic Uses of Sambucus nigra L. Extracts by the Assessment of the In Vitro and In Vivo Anti-Inflammatory Properties of Its PLGA …
AH Mota, N Duarte, AT Serra, A Ferreira, MR Bronze… - Pharmaceutics, 2020 - mdpi.com
Sambucus nigra L. is widely used in traditional medicine with different applications.
However, confirmative studies are strongly required. This study aimed to assess the …
However, confirmative studies are strongly required. This study aimed to assess the …
[HTML][HTML] Comparison of the analgesic efficacy of oral ketorolac versus intramuscular tramadol after third molar surgery: A parallel, double-blind, randomized, placebo …
MA Isiordia-Espinoza, A Pozos-Guillen… - … oral, patologia oral y …, 2016 - ncbi.nlm.nih.gov
Background Preemptive analgesia is considered an alternative for treating the postsurgical
pain of third molar removal. The aim of this study was to evaluate the preemptive analgesic …
pain of third molar removal. The aim of this study was to evaluate the preemptive analgesic …
Tramadol exposure upregulated apoptosis, inflammation and autophagy in PC12 cells and rat's striatum: An in vitro-in vivo approach
Aim and background Tramadol is a synthetic analogue of codeine, mostly prescribed for the
alleviation of mild to moderate pains. It bears several side effects including emotional …
alleviation of mild to moderate pains. It bears several side effects including emotional …
Variability in the analgesic response to ibuprofen is associated with cyclooxygenase activation in inflammatory pain
KN Theken, EV Hersh, NF Lahens… - Clinical …, 2019 - Wiley Online Library
The mechanisms underlying interindividual variability in analgesic efficacy of nonsteroidal
anti‐inflammatory drugs (NSAIDs) are not well understood. Therefore, we performed pain …
anti‐inflammatory drugs (NSAIDs) are not well understood. Therefore, we performed pain …
Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screening
G Chen, Y Xin, MM Hammour, B Braun, S Ehnert… - Archives of …, 2024 - Springer
Drug toxicity is an important cause of chronic liver damage, which in the long term can lead
to impaired bone homeostasis through an imbalance in the liver-bone axis. For instance …
to impaired bone homeostasis through an imbalance in the liver-bone axis. For instance …
Evidence‐based safety profile of oral ketorolac in adults: Systematic review and meta‐analysis
V Esparza‐Villalpando, G Ortiz‐Barroso… - Pharmacology …, 2024 - Wiley Online Library
The primary objective of the present review was to report the safety profile of oral ketorolac
in adults using the systematic review and meta‐analysis methodology based on clinical …
in adults using the systematic review and meta‐analysis methodology based on clinical …