Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …

Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

In dry age-related macular degeneration (AMD), LCN2 (lipocalin 2) is upregulated. Whereas
LCN2 has been implicated in AMD pathogenesis, the mechanism remains unknown. Here …

Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is
released by various cell types and is an attractive biomarker of inflammation, ischemia …

Objective Diets rich in fermentable fibres provide an array of health benefits; however, many
patients with IBD report poor tolerance to fermentable fibre-rich foods. Intervention studies …

Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

Lipocalin 2 (Lcn2), an innate immune protein, has emerged as a critical iron regulatory
protein during physiological and inflammatory conditions. As a bacteriostatic factor, Lcn2 …

Gut microbiota interacting with an intact mucosal surface are key to the maintenance of
homeostasis and health. This review discusses the current state of knowledge of the biofilm …

Aberrant liver sirtuin 1 (SIRT1), a mammalian NAD+-dependent protein deacetylase, is
implicated in the pathogenesis of alcoholic liver disease (ALD). However, the role of …