Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020 - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

Metabolomics biotechnology, applications, and future trends: a systematic review

Q Yang, A Zhang, J Miao, H Sun, Y Han, G Yan, F Wu… - RSC …, 2019 - pubs.rsc.org
Given the highly increased incidence of human diseases, a better understanding of the
related mechanisms regarding endogenous metabolism is urgently needed. Mass …

Beneficial effects of citrus flavanones naringin and naringenin and their food sources on lipid metabolism: An update on bioavailability, pharmacokinetics, and …

Y Yang, M Trevethan, S Wang, L Zhao - The Journal of nutritional …, 2022 - Elsevier
Naringin and naringin's aglycone naringenin belong to a subclass of flavonoids called
flavanones. While many studies of pure naringenin and naringin and their food sources …

Function, detection and alteration of acylcarnitine metabolism in hepatocellular carcinoma

S Li, D Gao, Y Jiang - Metabolites, 2019 - mdpi.com
Acylcarnitines play an essential role in regulating the balance of intracellular sugar and lipid
metabolism. They serve as carriers to transport activated long-chain fatty acids into …

Blood pressure and body fat% reduction is mainly related to flavanone phase II conjugates and minor extension by phenolic acid after long-term intake of orange juice

LN Fraga, CP Coutinho, AC Rozenbaum… - Food & function, 2021 - pubs.rsc.org
Hesperidin and narirutin are the major flavanones present in orange juice, and they are
associated with a reduction in risk of cardiometabolic disease. However, there is …

Recent advances in the application of metabolomics for nutrition and health

D González-Peña, L Brennan - Annual review of food science …, 2019 - annualreviews.org
Metabolomics is the study of small molecules called metabolites in biological samples.
Application of metabolomics to nutrition research has expanded in recent years, with …

Changes in plasma acylcarnitine and lysophosphatidylcholine levels following a high-fructose diet: a targeted metabolomics study in healthy women

A Gonzalez-Granda, A Damms-Machado, M Basrai… - Nutrients, 2018 - mdpi.com
Background: The consumption of high amounts of fructose is associated with metabolic
diseases. However, the underlying mechanisms are largely unknown. Objective: To …

Orange juice attenuates circulating miR-150-5p, miR-25-3p, and miR-451a in healthy smokers: a randomized crossover study

MS Dorna, EMS Barbosa, MA Callegari… - Frontiers in …, 2021 - frontiersin.org
Introduction: Tobacco smoke is associated with oxidative and inflammatory pathways,
increasing the risk of chronic-degenerative diseases. Our goal was to evaluate the effects of …

Plasma proteome profiling reveals molecular mechanisms underlying the effects of daily consumption of 'Bahia'and 'Cara Cara'orange juices

E de Castro Tobaruela, E Brasili, L Zeraik… - Food & Function, 2024 - pubs.rsc.org
Orange juice is an important food source of bioactive compounds, mainly the flavanones
hesperidin and narirutin. This study aimed to investigate the underlying molecular …

Effect of daily intake of a low-alcohol orange beverage on cardiovascular risk factors in hypercholesterolemic humans

I Cerrillo, B Escudero-López, A Ortega, F Martín… - Food Research …, 2019 - Elsevier
Oxidative stress, inflammation status, endothelial dysfunction, and imbalanced lipid
metabolism play a major role in cardiovascular disease. Bioactive compounds and …