Cancer chemoprevention and piperine: molecular mechanisms and therapeutic opportunities

RA Rather, M Bhagat - Frontiers in cell and developmental biology, 2018 - frontiersin.org
Cancer is a genetic disease characterized by unregulated growth and dissemination of
malignantly transformed neoplastic cells. The process of cancer development goes through …

[HTML][HTML] Piperine-a major principle of black pepper: a review of its bioactivity and studies

Z Stojanović-Radić, M Pejčić, M Dimitrijević, A Aleksić… - Applied Sciences, 2019 - mdpi.com
Piperine is the main compound present in black pepper, and is the carrier of its specific
pungent taste, which is responsible for centuries of human dietary utilization and worldwide …

Phytomedicine—Modulating oxidative stress and the tumor microenvironment for cancer therapy

YT Cheng, CC Yang, LF Shyur - Pharmacological research, 2016 - Elsevier
In spite of the current advances and achievements in systems biology and translational
medicinal research, the current strategies for cancer therapy, such as radiotherapy, targeted …

Anthocyanins from black peanut skin protect against UV-B induced keratinocyte cell and skin oxidative damage through activating Nrf 2 signaling

K Li, M Zhang, H Chen, J Peng, F Jiang, X Shi, Y Bai… - Food & function, 2019 - pubs.rsc.org
Excessive Ultraviolet (UV) irradiation induces skin damage. In the present study, the
potential protective activity of anthocyanins (cyanidin-3-O-sophoroside and cyanidin-3-O …

[HTML][HTML] Piperine attenuates UV-R induced cell damage in human keratinocytes via NF-kB, Bax/Bcl-2 pathway: An application for photoprotection

A Verma, HN Kushwaha, AK Srivastava… - … of Photochemistry and …, 2017 - Elsevier
Chronic ultraviolet radiation (UV-R) exposure causes skin disorders like erythema, edema,
hyperpigmentation, photoaging and photocarcinogenesis. Recent research trends of …

[PDF][PDF] Black Pepper, the “King of Spices”: Chemical composition to applications

B Hammouti, M Dahmani, A Yahyi… - Arab. J. Chem. Environ …, 2019 - mocedes.org
This article brings together an overview of the historical and scientific works on black pepper
(BP). It's well known as the king of spices, and literature which is very rich showing that it …

Targeting Peroxisome Proliferator-Activated Receptor-β/δ, Reactive Oxygen Species and Redox Signaling with Phytocompounds for Cancer Therapy

C Kaur, SK Sahu, K Bansal, LK DeLiberto… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Peroxisome proliferator-activated receptors (PPARs) have a moderately
preserved amino-terminal domain, an extremely preserved DNA-binding domain, an integral …

Gambogic Acid and Piperine Synergistically Induce Apoptosis in Human Cholangiocarcinoma Cell via Caspase and Mitochondria‐Mediated Pathway

R Yapasert, R Banjerdpongchai - … ‐Based Complementary and …, 2022 - Wiley Online Library
Most cholangiocarcinoma (CCA) patients undergo chemotherapy as a therapeutic approach
due to the disease's frequently late diagnosis. However, because CCA is resistant to …

Synthesis and anti-melanoma effect of 3-O-prenyl glycyrrhetinic acid against B16F10 cells via induction of endoplasmic reticulum stress-mediated autophagy through …

LA Nazir, NH Shahid, K Amit, SA Umar, S Rajni… - Frontiers in …, 2022 - frontiersin.org
Melanoma is an aggressive form of cancer with poor prognosis and survival rates and
limited therapeutic options. Here, we report the anti-melanoma effect of 3-O-prenyl …

[PDF][PDF] Clinical Uses of Piperine: A Review

G Bawa, N Khurana, A Singh - World J. Pharm. Res, 2021 - academia.edu
Main Substance of piper nigrum is Piperine having pungency that is accountable for
hundreds of clinical dietary utility and worldwide popularity as a food ingredient. It is act as a …