[HTML][HTML] Mini review: Genome mining approaches for the identification of secondary metabolite biosynthetic gene clusters in Streptomyces
Streptomyces are a large and valuable resource of bioactive and complex secondary
metabolites, many of which have important clinical applications. With the advances in high …
metabolites, many of which have important clinical applications. With the advances in high …
[HTML][HTML] Molecular and biotechnological aspects of secondary metabolites in actinobacteria
R Salwan, V Sharma - Microbiological research, 2020 - Elsevier
The ability to produce plethora of secondary metabolites and enzymes for pharmaceutical,
agricultural and biotechnological applications make actinobacteria one of the most explored …
agricultural and biotechnological applications make actinobacteria one of the most explored …
Global analysis of the biosynthetic chemical space of marine prokaryotes
Background Marine prokaryotes are a rich source of novel bioactive secondary metabolites
for drug discovery. Recent genome mining studies have revealed their great potential to bio …
for drug discovery. Recent genome mining studies have revealed their great potential to bio …
Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability
Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through
its interactions with growing and decaying flora and their constituent microbiomes. The …
its interactions with growing and decaying flora and their constituent microbiomes. The …
[HTML][HTML] Strategies to establish the link between biosynthetic gene clusters and secondary metabolites
I Kjærbølling, UH Mortensen, T Vesth… - Fungal Genetics and …, 2019 - Elsevier
Filamentous fungi produce a vast number of bioactive secondary metabolites (SMs), some of
which have found applications in the pharmaceutical industry including as antibiotics and …
which have found applications in the pharmaceutical industry including as antibiotics and …
Bioactive compounds as an alternative for the sugarcane industry: Towards an integrative approach
A Molina-Cortés, M Quimbaya, A Toro-Gomez… - Heliyon, 2023 - cell.com
Here, a comprehensive review of sugarcane industrialization and its relationship with
bioactive compounds (BCs) detected in various products and by-products generated during …
bioactive compounds (BCs) detected in various products and by-products generated during …
[HTML][HTML] Insights into applications and strategies for discovery of microbial bioactive metabolites
Secondary metabolites of microbial origin are structurally diverse and functionally versatile
compounds that offer selective advantages to the producing organism. Production of these …
compounds that offer selective advantages to the producing organism. Production of these …
Bioinformatic and reactivity-based discovery of linaridins
MA Georgiou, SR Dommaraju, X Guo… - ACS chemical …, 2020 - ACS Publications
Linaridins are members of the ribosomally synthesized and post-translationally modified
peptide (RiPP) family of natural products. Five linaridins have been reported, which are …
peptide (RiPP) family of natural products. Five linaridins have been reported, which are …
Genome In Silico and In Vitro Analysis of the Probiotic Properties of a Bacterial Endophyte, Bacillus Paranthracis Strain MHSD3
Spore-forming Bacillus species are gaining interest in human health recently, due to their
ability to withstand the harsh environment of the gastrointestinal tract. The present study …
ability to withstand the harsh environment of the gastrointestinal tract. The present study …
Structure elucidation and biosynthetic gene cluster analysis of caniferolides A–D, new bioactive 36-membered macrolides from the marine-derived Streptomyces …
I Pérez-Victoria, D Oves-Costales, R Lacret… - Organic & …, 2019 - pubs.rsc.org
Bioassay-guided isolation based on the antifungal activity of a culture broth of the marine-
derived actinomycete Streptomyces caniferus CA-271066 led to the discovery of new 36 …
derived actinomycete Streptomyces caniferus CA-271066 led to the discovery of new 36 …