The linear peptide gramicidin forms prototypical ion channels specific for monovalent
cations and has been extensively used to study the organization, dynamics and function of …

Studies of ion channels have for long been dominated by the animalcentric, if not
anthropocentric, view of physiology. The structures and activities of ion channels had …

Integral membrane proteins have central roles in a vast number of vital cellular processes. A
structural feature that most membrane proteins have in common is the presence of one or …

Sarcoendoplasmic reticulum calcium ATPase (SERCA), a member of the P-type ATPase
family of ion and lipid pumps, is responsible for the active transport of Ca2+ from the …

The interaction of l-phenylalanine with a 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine
(DPPC) monolayer at the air–water interface was explored using a combination of …

Inwardly rectifying potassium (Kir) channels play a key role in controlling membrane
potentials in excitable and unexcitable cells, thereby regulating a plethora of physiological …

We report biallelic missense and frameshift pathogenic variants in the gene encoding
human nucleoporin NUP214 causing acute febrile encephalopathy. Clinical symptoms …

Malfunction of hERG potassium channels, due to inherited mutations or inhibition by drugs,
can cause long QT syndrome, which can lead to life‐threatening arrhythmias. A three …

Biological membranes are complex assemblies of lipids and proteins that allow cellular
compartmentalization and act as the interface through which cells communicate with each …

In the present contribution, we investigate the interactions of lipid bilayer membranes of
different charges and different phase states with aliphatic amino acids of varying charge …