The signal pathways and treatment of cytokine storm in COVID-19
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …
and is more devastating than any other previous infectious disease. It has affected a …
COVID-19 therapeutics: Challenges and directions for the future
PC Robinson, DFL Liew, HL Tanner… - Proceedings of the …, 2022 - National Acad Sciences
The emergence of SARS-CoV-2 triggering the COVID-19 pandemic ranks as arguably the
greatest medical emergency of the last century. COVID-19 has highlighted health disparities …
greatest medical emergency of the last century. COVID-19 has highlighted health disparities …
Metabolic messengers: tumour necrosis factor
JK Sethi, GS Hotamisligil - Nature metabolism, 2021 - nature.com
Tumour necrosis factor (TNF) is a classical, pleiotropic pro-inflammatory cytokine. It is also
the first 'adipokine'described to be produced from adipose tissue, regulated in obesity and …
the first 'adipokine'described to be produced from adipose tissue, regulated in obesity and …
COVID-19 and diabetes mellitus: from pathophysiology to clinical management
Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …
[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19
JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
An inflammatory cytokine signature predicts COVID-19 severity and survival
DM Del Valle, S Kim-Schulze, HH Huang… - Nature medicine, 2020 - nature.com
Several studies have revealed that the hyper-inflammatory response induced by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease …
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …
200,000 deaths worldwide. Several studies have now established that the …
Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
Coronavirus disease 2019 (COVID-19) is characterized by distinct patterns of disease
progression that suggest diverse host immune responses. We performed an integrated …
progression that suggest diverse host immune responses. We performed an integrated …
[HTML][HTML] Endothelial cell infection and endotheliitis in COVID-19
Z Varga, AJ Flammer, P Steiger, M Haberecker… - The Lancet, 2020 - thelancet.com
Cardiovascular complications are rapidly emerging as a key threat in coronavirus disease
2019 (COVID-19) in addition to respiratory disease. The mechanisms underlying the …
2019 (COVID-19) in addition to respiratory disease. The mechanisms underlying the …
Corticosteroids, but not TNF antagonists, are associated with adverse COVID-19 outcomes in patients with inflammatory bowel diseases: results from an international …
Background and Aims The impact of Coronavirus disease 2019 (COVID-19) on patients with
inflammatory bowel disease (IBD) is unknown. We sought to characterize the clinical course …
inflammatory bowel disease (IBD) is unknown. We sought to characterize the clinical course …