Biosensors based on DNA logic gates

F Yin, F Wang, C Fan, X Zuo, Q Li - View, 2021 - Wiley Online Library
Abstract Biosensor is a device that responds to a particular target in a selective way by
incorporation of biological recognition as sensing unit. For practical biomedical applications …

A perspective of epigenetic regulation in radiotherapy

Q Peng, K Weng, S Li, R Xu, Y Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
Radiation therapy (RT) has been employed as a tumoricidal modality for more than 100
years and on 470,000 patients each year in the United States. The ionizing radiation causes …

Single-molecular Förster resonance energy transfer measurement on structures and interactions of biomolecules

Y Qiao, Y Luo, N Long, Y Xing, J Tu - Micromachines, 2021 - mdpi.com
Single-molecule Förster resonance energy transfer (smFRET) inherits the strategy of
measurement from the effective “spectroscopic ruler” FRET and can be utilized to observe …

Epigenetic regulation and mechanobiology

S Li, D Yang, L Gao, Y Wang, Q Peng - Biophysics Reports, 2020 - Springer
Mechanical force regulates a variety of cellular functions through inducing modulations in
nuclear chromatin structures and epigenetic landscapes (outside in). The epigenetic …

Ephrin or not? Six tough questions on Eph targeting

C Giorgio, I Zanotti, A Lodola… - Expert Opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction: The Eph-ephrin is a cell-cell communication system generating a
forward signal in cell expressing Eph receptors and a reverse signal in ephrin-ligand …

Detecting disruption of HER2 membrane protein organization in cell membranes with nanoscale precision

Y Moradi, JSH Lee, AM Armani - ACS sensors, 2023 - ACS Publications
The spatiotemporal organization of proteins within the cell membrane can affect numerous
biological functions, including cell signaling, communication, and transportation. Deviations …

Cellular plasticity during metastasis: new insights provided by intravital microscopy

AS Margarido, L Bornes… - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
Metastasis is a highly dynamic process during which cancer and microenvironmental cells
undergo a cascade of events required for efficient dissemination throughout the body …

Direct Quantification of Ligand‐Induced Lipid and Protein Microdomains with Distinctive Signaling Properties

D Wirth, MD Paul, EB Pasquale… - …, 2022 - Wiley Online Library
Lipid rafts are ordered lipid domains that are enriched in saturated lipids, such as the
ganglioside GM1. While lipid rafts are believed to exist in cells and to serve as signaling …

Radiation prevents tumor progression by inhibiting the miR‑93‑5p/EphA4/NF‑κB pathway in triple‑negative breast cancer

C Pan, S Shao, Y Gu, Q Ni - Oncology Reports, 2023 - spandidos-publications.com
Breast cancer (BC) is the most common type of cancer in women. Triple‑negative BC
(TNBC) constitutes 10‑15% of all BC cases and is associated with a poor prognosis. It has …

Frequency-dependent signaling in cardiac myocytes

P Haftbaradaran Esfahani, J Westergren… - Frontiers in …, 2022 - frontiersin.org
Background: Recent experimental data support the view that signaling activity at the
membrane depends on its geometric parameters such as surface area and curvature …