[HTML][HTML] A sex-and site-specific relationship between body mass index and osteoarthritis: evidence from observational and genetic analyses
L Zhang, W Zhang, X Wu, H Cui, P Yan, C Yang… - Osteoarthritis and …, 2023 - Elsevier
Objective We primarily aimed to investigate whether there are phenotypic and genetic links
underlying body mass index (BMI) and overall osteoarthritis (OA). We then intended to …
underlying body mass index (BMI) and overall osteoarthritis (OA). We then intended to …
Genetic Mechanisms Driving Uterine Leiomyoma Pathobiology, Epidemiology, and Treatment
MS Ramaiyer, E Saad, I Kurt, MA Borahay - Genes, 2024 - mdpi.com
Uterine leiomyomas (ULs) are the most common benign tumor of the uterus. They can be
associated with symptoms including abnormal uterine bleeding, pelvic pain, urinary …
associated with symptoms including abnormal uterine bleeding, pelvic pain, urinary …
Explainable multi-task learning improves the parallel estimation of polygenic risk scores for many diseases through shared genetic basis
Many complex diseases share common genetic determinants and are comorbid in a
population. We hypothesized that the co-occurrences of diseases and their overlapping …
population. We hypothesized that the co-occurrences of diseases and their overlapping …
Association between breast diseases and symptomatic uterine fibroids by using South Korean National Health Insurance database
Both the uterus and breasts have sex hormone dependence, yet there are few studies on the
association between breast disease and uterine fibroids (UFs). The purpose of this study …
association between breast disease and uterine fibroids (UFs). The purpose of this study …
Investigation of common genetic risk factors between thyroid traits and breast cancer
Breast cancer (BC) risk is suspected to be linked to thyroid disorders, however observational
studies exploring the association between BC and thyroid disorders gave conflicting results …
studies exploring the association between BC and thyroid disorders gave conflicting results …
Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis
BR Wang, J Wang, T Tian, SX Zhang, YQ Zhao… - Journal of Affective …, 2024 - Elsevier
Background and aims The comorbidity between bipolar disorder (BD) and inflammatory
bowel disease (IBD) has been widely reported in observational studies. However, unclear …
bowel disease (IBD) has been widely reported in observational studies. However, unclear …
Shared genetic basis and causality between schizophrenia and inflammatory bowel disease: evidence from a comprehensive genetic analysis
J Wang, GY Luo, T Tian, YQ Zhao, SY Meng… - Psychological …, 2024 - cambridge.org
BackgroundThe comorbidity between schizophrenia (SCZ) and inflammatory bowel disease
(IBD) observed in epidemiological studies is partially attributed to genetic overlap, but the …
(IBD) observed in epidemiological studies is partially attributed to genetic overlap, but the …
Association of fibroids, endometriosis, and gynecologic surgeries with breast cancer incidence and hormone receptor subtypes
Background: Fibroids and endometriosis are sex hormone–mediated and exhibit cancer-like
behavior. Breast cancer may be more common in women who have had these conditions …
behavior. Breast cancer may be more common in women who have had these conditions …
A cause-effect relationship between Uterine diseases and Breast cancer: A bidirectional Mendelian randomization study
Z Liu, M Jiang, T Wang, F Li, Y Zhu - Heliyon, 2024 - cell.com
Objective To explore the cause-effect relationship between uterine diseases (UDs) and
breast cancer (BC) and underlying mechanism of the cause-effect relationship, enhance …
breast cancer (BC) and underlying mechanism of the cause-effect relationship, enhance …
[HTML][HTML] A multi-level investigation of the genetic relationship between gastroesophageal reflux disease and lung cancer
D Wu, J Zhou, L Song, Q Zheng, T Wang… - Translational Lung …, 2024 - tlcr.amegroups.org
Background: Observational studies have revealed a potential association between
gastroesophageal reflux disease (GERD) and lung cancer (LC), but the genetic role in their …
gastroesophageal reflux disease (GERD) and lung cancer (LC), but the genetic role in their …