Diaryl ether: a privileged scaffold for drug and agrochemical discovery

T Chen, H Xiong, JF Yang, XL Zhu… - Journal of Agricultural …, 2020 - ACS Publications
Diaryl ether (DE) is a functional scaffold existing widely both in natural products (NPs) and
synthetic organic compounds. Statistically, DE is the second most popular and enduring …

Quaternary phosphonium salts in the synthetic chemistry: Recent progress, development, and future perspectives

N Noroozi-Shad, M Gholizadeh… - Journal of Molecular …, 2022 - Elsevier
Progress a chemical reaction through catalysis is a privileged approach that includes almost
95%(in volume) of all of the usual chemical compounds. Therefore investigation about high …

para‐Selective C−H Borylation of Aromatic Quaternary Ammonium and Phosphonium Salts

S Lu, T Zheng, J Ma, Z Deng, S Qin… - Angewandte …, 2022 - Wiley Online Library
Aromatic ammonium and phosphonium salts are important synthetic intermediates and
multifunctional materials, but para‐selective functionalization of the aromatic salts remains a …

Suzuki Coupling of Amides via Palladium‐Catalyzed C–N Cleavage of N‐Acylsaccharins

H Wu, Y Li, M Cui, J Jian, Z Zeng - Advanced Synthesis & …, 2016 - Wiley Online Library
A palladium‐catalyzed cross‐coupling of activated amides with arylboronic acids has been
developed via C–N bond cleavage. This approach demonstrated high tolerance to a variety …

TPP-based mitocans: A potent strategy for anticancer drug design

J Wang, J Li, Y Xiao, B Fu, Z Qin - RSC Medicinal Chemistry, 2020 - pubs.rsc.org
Cancer is one of the most important problems that endanger human health. The number of
cancer patients is increasing rapidly worldwide. Compared with normal cells, cancer cells …

Antimicrobial potential of quaternary phosphonium salt compounds: A review

MK Ibrahim, A Haria, NV Mehta… - Future Medicinal …, 2023 - Taylor & Francis
Given that mitochondrial dysregulation is a biomarker of many cancers, cationic quaternary
phosphonium salt (QPS) conjugation is a widely utilized strategy for anticancer drug design …

Synthesis and antibacterial activity of novel phosphonium salts on the basis of pyridoxine

MV Pugachev, NV Shtyrlin, LP Sysoeva… - Bioorganic & medicinal …, 2013 - Elsevier
A series of 13 phosphonium salts on the basis of pyridoxine derivatives were synthesized
and their antibacterial activity against clinically relevant strains was tested in vitro. All …

Metal–Micelle Interaction Leading to Spontaneous Formation of Ligand-Free Palladium (0) Nanoparticles: Highly Efficient Catalysis Enabling Biaryl Ketone Formation …

G Kaur, JB Jasinski, F Gallou… - ACS Applied Materials & …, 2022 - ACS Publications
A novel strategy has been developed to spontaneously form ligand-free Pd (0) nanoparticles
(NPs) from water-and air-sensitive Pd2dba3 in water. These NPs are thoroughly …

Trypanocidal Mechanism of Action and in silico Studies of p-Coumaric Acid Derivatives

SP Lopes, YP Castillo, ML Monteiro… - International journal of …, 2019 - mdpi.com
Trypanosoma species are responsible for chronic and systemic infections in millions of
people around the world, compromising life quality, and family and government budgets …

Shifting from Ammonium to Phosphonium Salts: A Promising Strategy to Develop Next-Generation Weapons against Biofilms

S Alfei - Pharmaceutics, 2024 - mdpi.com
Since they are difficult and sometimes impossible to treat, infections sustained by multidrug-
resistant (MDR) pathogens, emerging especially in nosocomial environments, are an …