A comprehensive survey of integron-associated genes present in metagenomes

M Buongermino Pereira, T Österlund, KM Eriksson… - BMC genomics, 2020 - Springer
Background Integrons are genomic elements that mediate horizontal gene transfer by
inserting and removing genetic material using site-specific recombination. Integrons are …

[HTML][HTML] Elucidation of Proteus mirabilis as a key bacterium in Crohn's disease inflammation

J Zhang, EC Hoedt, Q Liu, E Berendsen, JJ Teh… - Gastroenterology, 2021 - Elsevier
Background & Aims Proteus spp, Gram-negative facultative anaerobic bacilli, have recently
been associated with Crohn's disease (CD) recurrence after intestinal resection. We …

Extensive screening reveals previously undiscovered aminoglycoside resistance genes in human pathogens

D Lund, RD Coertze, M Parras-Moltó… - Communications …, 2023 - nature.com
Antibiotic resistance is a growing threat to human health, caused in part by pathogens
accumulating antibiotic resistance genes (ARGs) through horizontal gene transfer. New …

The impact of primer design on amplicon-based metagenomic profiling accuracy: detailed insights into bifidobacterial community structure

L Mancabelli, C Milani, GA Lugli, F Fontana, F Turroni… - Microorganisms, 2020 - mdpi.com
Next Generation Sequencing (NGS) technologies have overcome the limitations of
cultivation-dependent approaches and allowed detailed study of bacterial populations that …

Coupling machine learning and high throughput multiplex digital PCR enables accurate detection of carbapenem-resistant genes in clinical isolates

L Miglietta, A Moniri, I Pennisi… - Frontiers in molecular …, 2021 - frontiersin.org
Rapid and accurate identification of patients colonised with carbapenemase-producing
organisms (CPOs) is essential to adopt prompt prevention measures to reduce the risk of …

Global distribution patterns of carbapenemase-encoding bacteria in a new light: Clues on a role for ethnicity

C Neidhöfer, C Buechler, G Neidhöfer… - Frontiers in Cellular …, 2021 - frontiersin.org
Antibiotic resistance represents a major global concern. The rapid spread of
opportunistically pathogenic carbapenemase-encoding bacteria (CEB) requires clinicians …

Responses of carbapenemase-producing and non-producing carbapenem-resistant Pseudomonas aeruginosa strains to meropenem revealed by quantitative …

F Salvà-Serra, D Jaén-Luchoro, NP Marathe… - Frontiers in …, 2023 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen with increasing incidence of
multidrug-resistant strains, including resistance to last-resort antibiotics, such as …

Mobilome and Resistome Reconstruction from Genomes Belonging to Members of the Bifidobacterium Genus

W Mancino, GA Lugli, D van Sinderen, M Ventura… - Microorganisms, 2019 - mdpi.com
Specific members of the genus Bifidobacterium are among the first colonizers of the
human/animal gut, where they act as important intestinal commensals associated with host …

Interest of bacterial pangenome analyses in clinical microbiology

H Anani, R Zgheib, I Hasni, D Raoult, PE Fournier - Microbial pathogenesis, 2020 - Elsevier
Thanks to the progress and decreasing costs in genome sequencing technologies, more
than 250,000 bacterial genomes are currently available in public databases, covering most …

[HTML][HTML] Carbapenem resistant organisms: A 9-year surveillance and trends at Saint George University Medical Center

A Chamieh, G El-Hajj, O Zmerli, C Afif, E Azar - Journal of infection and …, 2020 - Elsevier
Introduction Carbapenem resistant organisms (CRO) constitute a large group of bacteria
with different mechanisms of resistance and recently increasing global incidence. This rise …