Proposed multidimensional pain outcome methodology to demonstrate analgesic drug efficacy and facilitate future drug approval for piglet castration

A Baysinger, SR Webb, J Brown… - Animal Health …, 2021 - cambridge.org
Castration of male piglets in the United States is conducted without analgesics because no
Food and Drug Administration (FDA) approved products are labeled for pain control in …

Validation of the Unesp-Botucatu pig composite acute pain scale (UPAPS) in piglets undergoing castration

I Robles, SPL Luna, PHE Trindade, M Lopez-Soriano… - PloS one, 2023 - journals.plos.org
To accurately assess pain and support broadly-based analgesic protocols to mitigate swine
pain, it is imperative to develop and validate a species-specific pain scale. The objective of …

Non-steroidal anti-inflammatory drugs: Pharmacokinetics and mitigation of procedural-pain in cattle

BK Wagner, E Nixon, I Robles, RE Baynes, JF Coetzee… - Animals, 2021 - mdpi.com
Simple Summary Castration and disbudding, common husbandry procedures used in cattle
livestock production industries, are recognized as being painful. In the United States (US) …

Pain in pigs: Characterisation and indicators

MS Herskin, P Di Giminiani - Advances in Pig Welfare, 2024 - Elsevier
Pain is a perceptional phenomenon built from information gathered by specialised sensory
receptors for tissue damage, modified by ascending and descending spinal and supraspinal …

[HTML][HTML] Development of a highly reproducible GC-HRMS method for determination of Skatole in pig tissues

AE Afe, Z Shen, X Guo, W Xing, K Li, R Zhou - Food Chemistry: X, 2024 - Elsevier
This study presents a sensitive and reproducible mass spectrometry method for quantifying
skatole in porcine adipose tissue, muscle, and serum samples applicable for abattoirs and …

[HTML][HTML] Validation of behavioural sampling techniques for 20-25 kg pigs during transport

C Kobek-Kjeldager, LD Jensen, L Foldager, M Kaiser… - Livestock Science, 2024 - Elsevier
Monitoring behaviour during transport is challenging due to the design of vehicles and often
limited deck height. The aim of the present study was to validate behavioural sampling …

Evaluating accurate and efficient sampling strategies designed to measure social behavior and brush use in drylot housed cattle

CC Lozada, RM Park, CL Daigle - Plos one, 2023 - journals.plos.org
Efficient sampling strategies expedite behavioral data collection. While multiple studies have
evaluated sampling strategies for core behaviors in cattle, few have focused on social …

[HTML][HTML] Administration of procaine-based local anaesthetic prior to surgical castration influences post-operative behaviours of piglets

M Coutant, J Malmkvist, C Tallet, CJA Williams… - Applied Animal …, 2023 - Elsevier
In an effort to mitigate piglet acute responses to surgical castration, the procedure can be
preceded by injections of a local anaesthetic. Regardless of potential benefits at castration …

Observing brief and irregular behaviour of animals—The validity of short observation Periods

T Wilder, J Krieter, N Kemper, K Büttner - Applied Sciences, 2021 - mdpi.com
There are efficient sampling methods to accurately estimate behaviour with a moderate or
long duration. For short behaviour, observing animals continuously is recommended …

Technical contribution: use of continuous recording video monitoring of maintenance and pain behaviors in piglets after surgical castration to validate six continuous …

I Robles, RM Park, CM Cramer… - Journal of Animal …, 2021 - academic.oup.com
Castration is a painful procedure routinely performed on piglets. Specific periods relative to
castration and time sampling rules are used widely to quantify deviations in piglet's behavior …