Bioinformatic analysis of large and complex omics datasets has become increasingly useful
in modern day biology by providing a great depth of information, with its application to …

Neurological conditions are the leading cause of disability and mortality combined,
demanding innovative, scalable, and sustainable solutions. Brain health has become a …

Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic
heterogeneity. Machine learning approaches have previously been utilised for patient …

Since its initial involvement in numerous neurodegenerative pathologies in 2006, either as a
principal actor or as a cofactor, new pathologies implicating transactive response (TAR) …

Increasing evidence suggests an essential function for autophagy in unconventional protein
secretion (UPS). However, despite its relevance for the secretion of aggregate-prone …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder and the most common
motor neuron disease. ALS shows substantial clinical and molecular heterogeneity. In vitro …

Spinal motor neurons (MNs) represent a highly vulnerable cellular population, which is
affected in fatal neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) …

Substantial advances in technology are permitting a high resolution understanding of the
salience of glia, and have helped us to transcend decades of predominantly neuron‐centric …

Typical multiomics studies employ separate methods for DNA, RNA, and protein sample
preparation, which is labor intensive, costly, and prone to sampling bias. We describe a …

Background Stem cell research, particularly in the domain of induced pluripotent stem cell
(iPSC) technology, has shown significant progress. The integration of artificial intelligence …