A family of facilitative glucose transporters (GLUTs) is involved in regulating tissue-specific
glucose uptake and metabolism in the liver, skeletal muscle, and adipose tissue to ensure …

Solute carriers of the glucose transporter (GLUT) family mediate the first step for cellular
glucose usage. The upregulation of GLUT s has been reported in numerous cancer types as …

The protein family of facilitative glucose transporters comprises 14 isoforms that share
common structural features such as 12 transmembrane domains, N‐and C‐termini facing …

Male infertility is approaching a concerning prevalence worldwide, and inflicts various
impacts on the affected couple. The hormonal assessment is a vital component of male …

Mouse sperm produce enough ATP to sustain motility by anaerobic glycolysis and
respiration. However, previous studies indicated that an active glycolytic pathway is required …

Lysosomes are cellular organelles that function to catabolize both extra-and intracellular
cargo, act as a platform for nutrient sensing, and represent a core signaling node integrating …

Spermiogenesis is a long process whereby haploid spermatids derived from the meiotic
divisions of spermatocytes undergo metamorphosis into spermatozoa. It is subdivided into …

Facilitative sugar transporters (GLUTs) are the primary method of sugar uptake in all
mammalian cells. There are 14 different types of those transmembrane proteins, but they …

Infertility is prevalent in about 10%-25% of couples in their reproductive age, analogous to
60-80 million infertile couples globally. Of these infertility cases, 10%-30% are exclusively …

GLUT8 is a class III sugar transporter predominantly expressed in testis and brain. In
contrast to the class I and class II transporters, hydrophobicity plots predict a short …