The roles of matrix metalloproteinases and their inhibitors in human diseases

GA Cabral-Pacheco, I Garza-Veloz… - International journal of …, 2020 - mdpi.com
Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM)
remodeling endopeptidases that have the capacity to degrade almost every component of …

Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification

M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Endometrial function in women with polycystic ovary syndrome: a comprehensive review

S Palomba, TT Piltonen… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

[HTML][HTML] Epidemiology of ovarian cancer: a review

BM Reid, JB Permuth, TA Sellers - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the
world and the tenth most common in China. Epithelial OC is the most predominant …

Nutrition strategy and life style in polycystic ovary syndrome—Narrative review

M Szczuko, J Kikut, U Szczuko, I Szydłowska… - Nutrients, 2021 - mdpi.com
Here we present an extensive narrative review of the broadly understood modifications to
the lifestyles of women with polycystic ovary syndrome (PCOS). The PubMed database was …

Polycystic ovary syndrome

R Azziz, E Carmina, ZJ Chen, A Dunaif… - Nature reviews Disease …, 2016 - nature.com
Polycystic ovary syndrome (PCOS) affects 5–20% of women of reproductive age worldwide.
The condition is characterized by hyperandrogenism, ovulatory dysfunction and polycystic …

The pathogenesis of polycystic ovary syndrome (PCOS): the hypothesis of PCOS as functional ovarian hyperandrogenism revisited

RL Rosenfield, DA Ehrmann - Endocrine reviews, 2016 - academic.oup.com
Polycystic ovary syndrome (PCOS) was hypothesized to result from functional ovarian
hyperandrogenism (FOH) due to dysregulation of androgen secretion in 1989–1995 …

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

F Day, T Karaderi, MR Jones, C Meun, C He… - PLoS …, 2018 - journals.plos.org
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism,
ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have …

[HTML][HTML] Criteria, prevalence, and phenotypes of polycystic ovary syndrome

D Lizneva, L Suturina, W Walker, S Brakta… - Fertility and sterility, 2016 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly prevalent disorder effecting reproductive-
aged women worldwide. This article addresses the evolution of the criteria used to diagnosis …

Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis

M Dapas, FTJ Lin, GN Nadkarni, R Sisk, RS Legro… - PLoS …, 2020 - journals.plos.org
Background Polycystic ovary syndrome (PCOS) is a common, complex genetic disorder
affecting up to 15% of reproductive-age women worldwide, depending on the diagnostic …