Topography: a biophysical approach to direct the fate of mesenchymal stem cells in tissue engineering applications

X Cun, L Hosta-Rigau - Nanomaterials, 2020 - mdpi.com
Tissue engineering is a promising strategy to treat tissue and organ loss or damage caused
by injury or disease. During the past two decades, mesenchymal stem cells (MSCs) have …

Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

R Menezes, R Vincent, L Osorno, P Hu, TL Arinzeh - Acta biomaterialia, 2023 - Elsevier
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …

Effects of different cross-linking conditions on the properties of genipin-cross-linked chitosan/collagen scaffolds for cartilage tissue engineering

L Bi, Z Cao, Y Hu, Y Song, L Yu, B Yang, J Mu… - Journal of Materials …, 2011 - Springer
A cross-linking reagent is required to improve mechanical strength and degradation
properties of biopolymers for tissue engineering. To find the optimal preparative method, we …

[HTML][HTML] Strategies to minimize hypertrophy in cartilage engineering and regeneration

S Chen, P Fu, R Cong, HS Wu, M Pei - Genes & diseases, 2015 - Elsevier
Due to a blood supply shortage, articular cartilage has a limited capacity for self-healing
once damaged. Articular chondrocytes, cartilage progenitor cells, embryonic stem cells, and …

Regeneration of meniscus tissue using adipose mesenchymal stem cells-chondrocytes co-culture on a hybrid scaffold: In vivo study

L Moradi, M Vasei, MM Dehghan, M Majidi… - Biomaterials, 2017 - Elsevier
The meniscus has poor intrinsic regenerative capacity and its damage inevitably leads to
articular cartilage degeneration. We focused on evaluating the effects of Polyvinyl …

In vivo ectopic chondrogenesis of BMSCs directed by mature chondrocytes

X Liu, H Sun, D Yan, L Zhang, X Lv, T Liu, W Zhang… - Biomaterials, 2010 - Elsevier
In vivo niche plays an important role in determining the fate of exogenously implanted stem
cells. Due to the lack of a proper chondrogenic niche, stable ectopic chondrogenesis of …

Polymer microcapsules and microbeads as cell carriers for in vivo biomedical applications

B Kupikowska-Stobba, D Lewińska - Biomaterials science, 2020 - pubs.rsc.org
Polymer microcarriers are being extensively explored as cell delivery vehicles in cell-based
therapies and hybrid tissue and organ engineering. Spherical microcarriers are of particular …

Functional biomaterials for cartilage regeneration

Z Ge, C Li, BC Heng, G Cao… - Journal of biomedical …, 2012 - Wiley Online Library
The injury and degeneration of articular cartilage and associated arthritis are leading causes
of disability worldwide. Cartilage tissue engineering as a treatment modality for cartilage …

Substrate topography determines the fate of chondrogenesis from human mesenchymal stem cells resulting in specific cartilage phenotype formation

YN Wu, JBK Law, AY He, HY Low, JHP Hui… - … , Biology and Medicine, 2014 - Elsevier
To reproduce a complex and functional tissue, it is crucial to provide a biomimetic cellular
microenvironment that not only incorporates biochemical cues, but also physical features …

Human umbilical cord Wharton's jelly stem cells undergo enhanced chondrogenic differentiation when grown on nanofibrous scaffolds and in a sequential two-stage …

CY Fong, A Subramanian, K Gauthaman… - Stem Cell Reviews and …, 2012 - Springer
The current treatments used for osteoarthritis from cartilage damage have their
disadvantages of donor site morbidity, complicated surgical interventions and risks of …