It was shown as long as half a century ago that bone marrow is a source of not only
hematopoietic stem cells, but also stem cells of mesenchymal tissues. Then the term …

Mesenchymal stem cell (MSC)-sourced secretome, defined as the set of MSC-derived
bioactive factors (soluble proteins, nucleic acids, lipids and extracellular vesicles), showed …

Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …

Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …

Spinal cord injury (SCI) is a complex tissue injury resulting in permanent and degenerating
damage to the central nervous system (CNS). Detrimental cellular processes occur after SCI …

Mesenchymal stromal cells (MSCs) are characterized by a regulatory phenotype and
respond promptly to the environmental signals modulating their secretory activity. An …

Mesenchymal stem cells (MSCs) are multipotent tissue stem cells that differentiate into a
number of mesodermal tissue types, including osteoblasts, adipocytes, chondrocytes and …

Therapeutic treatment options for central nervous system diseases are greatly limited by the
blood-brain barrier (BBB). Focused ultrasound (FUS), in conjunction with circulating …

Extracellular ATP is a signaling molecule exploited by the immune cells for both autocrine
regulation and paracrine communication. By performing live calcium imaging experiments …

A significant number of clinical trials have been undertaken to explore the use of
mesenchymal stem cells (MSCs) for the treatment of several diseases such as Crohn's …