Introduction: Western blotting is one of the most commonly used techniques in molecular
biology and proteomics. Since western blotting is a multistep protocol, variations and errors …

Once focused mainly on the characterization of neoplasms, immunohistochemistry (IHC)
today is used in the investigation of a broad range of disease processes with applications in …

Western blotting is a technique that has been in practice for more than three decades that
began as a means of detecting a protein target in a complex sample. Although there have …

Well preserved frozen biospecimens are ideal for evaluating the genome, transcriptome,
and proteome. While papers reviewing individual aspects of frozen biospecimens are …

Oncotype DX is a commercial assay frequently used for making chemotherapy decisions in
estrogen receptor (ER)-positive breast cancers. The result is reported as a recurrence score …

Objective To harmonize standard operating procedures (SOPs) and standardize the
recording of associated data for collection, processing, and storage of human tissues …

Epitranscriptomic features, such as single-base RNA editing, are sources of transcript
diversity in cancer, but little is understood in terms of their spatial context in the tumour …

Although the search for disease biomarkers continues, the clinical return has thus far been
disappointing. The complexity of the body's response to disease makes it difficult to …

Endometrial cancer is the most common gynecologic neoplasm in developed countries;
however, updated universal guidelines are currently not available to handle specimens …

Introduction Very few studies have investigated whether the time elapsed between surgical
resection and tissue fixation or the difference between core-cut and excision biopsies impact …