Abstract Background and Objective Psychotropic drugs are a heterogenous group of
treatments prescribed for many psychiatric disorders, often for long periods. Their effects on …

For over half a century, it has been widely known that lithium is the most efficacious
maintenance treatment for bipolar disorder. Despite thorough research on the long-term …

Objectives To understand treatment practices for bipolar disorders (BD), this study leveraged
the Global Bipolar Cohort collaborative network to investigate pharmacotherapeutic …

Lithium has been a cornerstone treatment for bipolar disorder (BD). Despite descriptions in
the literature regarding associations between long-term lithium therapy (LTLT) and …

Lithium augmentation was reported in the 1980s to be effective in treating depressed
patients who failed to respond to tricyclic antidepressants (TCAs). 1, 2 Recent studies …

Background Lithium is well recognized as the first-line maintenance treatment for bipolar
disorder (BD). However, besides therapeutic benefits attributed to lithium therapy, the …

Purpose Long-term lithium therapy (LTLT) has been associated with chronic kidney disease
(CKD). We investigated changes in clinical characteristics, pharmacotherapeutic treatments …

Objectives Although potential adverse effects of lithium treatment on renal and endocrine
systems have been extensively investigated, most prior studies are limited by selected …

Introduction People with severe mental health difficulties (SMHDs) and concurrent kidney
disease have less access to quality kidney care and worse clinical outcomes. Our research …

Abstract Aims Lithium is Food and Drug Administration‐approved for bipolar disorder (BD)
and is also used in depressive disorders but is underutilized due to concerns about chronic …