Streptococcus pyogenes: Pathogenesis and the Current Status of Vaccines

J Wang, C Ma, M Li, X Gao, H Wu, W Dong, L Wei - Vaccines, 2023 - mdpi.com
Streptococcus pyogenes (group A Streptococcus; GAS), a Gram-positive coccal bacterium,
poses a significant global disease burden, especially in low-and middle-income countries …

Antibiotic resistance: a global crisis, problems and solutions

R Aggarwal, P Mahajan, S Pandiya… - Critical Reviews in …, 2024 - Taylor & Francis
Healthy state is priority in today's world which can be achieved using effective medicines.
But due to overuse and misuse of antibiotics, a menace of resistance has increased in …

Association of novel locus with rheumatic heart disease in Black African individuals: findings from the RHDGen study

T Machipisa, M Chong, B Muhamed, C Chishala… - JAMA …, 2021 - jamanetwork.com
Importance Rheumatic heart disease (RHD), a sequela of rheumatic fever characterized by
permanent heart valve damage, is the leading cause of cardiac surgery in Africa. However …

Conserved molecular chaperone PrsA stimulates protective immunity against group A Streptococcus

CY Lai, JX Xie, MC Lai, ZY Wu, JS Lin, YT Huang… - npj Vaccines, 2024 - nature.com
Abstract Group A Streptococcus (GAS) is a significant human pathogen that poses a global
health concern. However, the development of a GAS vaccine has been challenging due to …

Dendritic cell targeting peptide plus Salmonella FliCd flagellin fused outer membrane protein H (OmpH) demonstrated increased efficacy against infections caused by …

Z Wang, M Wang, F Wang, Y Luo, H Liu, Z Zhu… - Vaccine, 2024 - Elsevier
As the major outer membrane protein (OMP) presents in the Pasteurella multocida
envelope, OmpH was frequently expressed for laboratory assessments of its immunogenicity …

[HTML][HTML] Group A Streptococcus Infections: Their Mechanisms, Epidemiology, and Current Scope of Vaccines

V Iyer, V Sagar, D Toor, V Lyngdoh, G Nongrum… - Cureus, 2022 - ncbi.nlm.nih.gov
Group A streptococci (GAS) are gram-positive, cocci-shaped bacteria that cause a wide
variety of infections and are a cause of significant health burden, particularly in lower-and …

[PDF][PDF] Effect of Superantigen on Detecting Group A Streptococcus Specific T Cell Responses

EOEE Olanrewaju - 2023 - research-information.bris.ac.uk
Streptococcus pyogenes, also known as Group A Streptococcus (GAS), causes a wide
variety of clinical manifestations. An effective GAS vaccine would significantly reduce …