Drug resistance in colorectal cancer: An epigenetic overview
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Despite
significant progress that has been made in therapies against CRC over the past decades …
significant progress that has been made in therapies against CRC over the past decades …
Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer
Z Liu, L Liu, S Weng, C Guo, Q Dang, H Xu… - Nature …, 2022 - nature.com
Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in
colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs …
colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs …
Small non-coding RNAs in human cancer
Q Xiong, Y Zhang, J Li, Q Zhu - Genes, 2022 - mdpi.com
Small non-coding RNAs are widespread in the biological world and have been extensively
explored over the past decades. Their fundamental roles in human health and disease are …
explored over the past decades. Their fundamental roles in human health and disease are …
Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer
Z Liu, CG Guo, Q Dang, L Wang, L Liu, S Weng, H Xu… - …, 2022 - thelancet.com
Summary Background Long non-coding RNAs (lncRNAs) have recently emerged as
essential biomarkers of cancer progression. However, studies are limited regarding …
essential biomarkers of cancer progression. However, studies are limited regarding …
Identification of molecular subtypes and a novel prognostic model of diffuse large B-cell lymphoma based on a metabolism-associated gene signature
J He, Z Chen, Q Xue, P Sun, Y Wang, C Zhu… - Journal of Translational …, 2022 - Springer
Background Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma in
adults. Metabolic reprogramming in tumors is closely related to the immune …
adults. Metabolic reprogramming in tumors is closely related to the immune …
UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma
J Zhu, H Ao, M Liu, K Cao, J Ma - Journal of Translational Medicine, 2021 - Springer
Background Ubiquitin-conjugating enzyme E2T (UBE2T) acts as an oncogene in various
types of cancer. However, the mechanisms behind its oncogenic role remain unclear in lung …
types of cancer. However, the mechanisms behind its oncogenic role remain unclear in lung …
Predicting cancer prognosis and drug response from the tumor microbiome
LC Hermida, EM Gertz, E Ruppin - Nature communications, 2022 - nature.com
Tumor gene expression is predictive of patient prognosis in some cancers. However, RNA-
seq and whole genome sequencing data contain not only reads from host tumor and normal …
seq and whole genome sequencing data contain not only reads from host tumor and normal …
m6A modified BACE1-AS contributes to liver metastasis and stemness-like properties in colorectal cancer through TUFT1 dependent activation of Wnt signaling
X Wang, Y Liu, M Zhou, L Yu, Z Si - Journal of Experimental & Clinical …, 2023 - Springer
Background Liver metastasis is one of the most important reasons for high mortality of
colorectal cancer (CRC). Growing evidence illustrates that lncRNAs play a critical role in …
colorectal cancer (CRC). Growing evidence illustrates that lncRNAs play a critical role in …
Upregulation of LINC00501 by H3K27 acetylation facilitates gastric cancer metastasis through activating epithelial‐mesenchymal transition and angiogenesis
R Dou, L Han, C Yang, Y Fang, J Zheng… - Clinical and …, 2023 - Wiley Online Library
Background The molecular mechanism of the significant role of long noncoding RNAs
(lncRNAs) in the progression and metastasis of gastric cancer (GC) remains largely elusive …
(lncRNAs) in the progression and metastasis of gastric cancer (GC) remains largely elusive …
Incorporating Novel Technologies in Precision Oncology for Colorectal Cancer: Advancing Personalized Medicine
Simple Summary Cancer affects millions of individuals every year, with colorectal cancer
being among the most common. There is an increased need to identify new biomarkers that …
being among the most common. There is an increased need to identify new biomarkers that …