[HTML][HTML] The unique molecular and cellular microenvironment of ovarian cancer
T Worzfeld, E Pogge von Strandmann, M Huber… - Frontiers in …, 2017 - frontiersin.org
The reciprocal interplay of cancer cells and host cells is an indispensable prerequisite for
tumor growth and progression. Cells of both the innate and adaptive immune system, in …
tumor growth and progression. Cells of both the innate and adaptive immune system, in …
[HTML][HTML] The ovarian cancer tumor immune microenvironment (TIME) as target for therapy: a focus on innate immunity cells as therapeutic effectors
Ovarian cancer (OvCA) accounts for one of the leading causes of death from gynecologic
malignancy. Despite progress in therapy improvements in OvCA, most patients develop a …
malignancy. Despite progress in therapy improvements in OvCA, most patients develop a …
[HTML][HTML] Evaluating cell lines as tumour models by comparison of genomic profiles
Cancer cell lines are frequently used as in vitro tumour models. Recent molecular profiles of
hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour …
hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour …
Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases
Epithelial ovarian cancer has the highest mortality rate of any gynecologic malignancy and
most frequently metastasizes to the peritoneal cavity. Intraperitoneal metastases are highly …
most frequently metastasizes to the peritoneal cavity. Intraperitoneal metastases are highly …
Chemotherapy response score: development and validation of a system to quantify histopathologic response to neoadjuvant chemotherapy in tubo-ovarian high …
S Böhm, A Faruqi, I Said, M Lockley… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To develop and validate a histopathologic scoring system for measuring response
to neoadjuvant chemotherapy in interval debulking surgery specimens of stage IIIC to IV …
to neoadjuvant chemotherapy in interval debulking surgery specimens of stage IIIC to IV …
LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth
N Zhang, SH Kim, A Gainullina, EC Erlich… - Journal of Experimental …, 2021 - rupress.org
Two resident macrophage subsets reside in peritoneal fluid. Macrophages also reside within
mesothelial membranes lining the peritoneal cavity, but they remain poorly characterized …
mesothelial membranes lining the peritoneal cavity, but they remain poorly characterized …
Murine CD27(−) Vγ6(+) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages
M Rei, N Gonçalves-Sousa, T Lança… - Proceedings of the …, 2014 - National Acad Sciences
Cancer-associated inflammation mobilizes a variety of leukocyte populations that can inhibit
or enhance tumor cell growth in situ. These subsets include γδ T cells, which can infiltrate …
or enhance tumor cell growth in situ. These subsets include γδ T cells, which can infiltrate …
[HTML][HTML] Fatty acid metabolism in ovarian cancer: Therapeutic implications
H Yoon, S Lee - International Journal of Molecular Sciences, 2022 - mdpi.com
Ovarian cancer is the most malignant gynecological tumor. Previous studies have reported
that metabolic alterations resulting from deregulated lipid metabolism promote ovarian …
that metabolic alterations resulting from deregulated lipid metabolism promote ovarian …
[HTML][HTML] The crowded crosstalk between cancer cells and stromal microenvironment in gynecological malignancies: biological pathways and therapeutic implication
The tumor microenvironment plays a pillar role in the progression and the distance
dissemination of cancer cells in the main malignancies affecting women—epithelial ovarian …
dissemination of cancer cells in the main malignancies affecting women—epithelial ovarian …
[HTML][HTML] Prognostic and predictive role of tumor-infiltrating lymphocytes (TILs) in ovarian cancer
D Fanale, A Dimino, E Pedone, C Brando, LR Corsini… - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present current knowledge about the prognostic and
predictive role of tumor-infiltrating lymphocytes (TILs) in ovarian cancer since this tumor …
predictive role of tumor-infiltrating lymphocytes (TILs) in ovarian cancer since this tumor …