[HTML][HTML] The unique molecular and cellular microenvironment of ovarian cancer

T Worzfeld, E Pogge von Strandmann, M Huber… - Frontiers in …, 2017 - frontiersin.org
The reciprocal interplay of cancer cells and host cells is an indispensable prerequisite for
tumor growth and progression. Cells of both the innate and adaptive immune system, in …

[HTML][HTML] The ovarian cancer tumor immune microenvironment (TIME) as target for therapy: a focus on innate immunity cells as therapeutic effectors

D Baci, A Bosi, M Gallazzi, M Rizzi, DM Noonan… - International journal of …, 2020 - mdpi.com
Ovarian cancer (OvCA) accounts for one of the leading causes of death from gynecologic
malignancy. Despite progress in therapy improvements in OvCA, most patients develop a …

[HTML][HTML] Evaluating cell lines as tumour models by comparison of genomic profiles

S Domcke, R Sinha, DA Levine, C Sander… - Nature …, 2013 - nature.com
Cancer cell lines are frequently used as in vitro tumour models. Recent molecular profiles of
hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour …

Omentum-on-a-chip: A multicellular, vascularized microfluidic model of the human peritoneum for the study of ovarian cancer metastases

LI Ibrahim, C Hajal, GS Offeddu, MR Gillrie, RD Kamm - Biomaterials, 2022 - Elsevier
Epithelial ovarian cancer has the highest mortality rate of any gynecologic malignancy and
most frequently metastasizes to the peritoneal cavity. Intraperitoneal metastases are highly …

Chemotherapy response score: development and validation of a system to quantify histopathologic response to neoadjuvant chemotherapy in tubo-ovarian high …

S Böhm, A Faruqi, I Said, M Lockley… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To develop and validate a histopathologic scoring system for measuring response
to neoadjuvant chemotherapy in interval debulking surgery specimens of stage IIIC to IV …

LYVE1+ macrophages of murine peritoneal mesothelium promote omentum-independent ovarian tumor growth

N Zhang, SH Kim, A Gainullina, EC Erlich… - Journal of Experimental …, 2021 - rupress.org
Two resident macrophage subsets reside in peritoneal fluid. Macrophages also reside within
mesothelial membranes lining the peritoneal cavity, but they remain poorly characterized …

Murine CD27(−) Vγ6(+) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages

M Rei, N Gonçalves-Sousa, T Lança… - Proceedings of the …, 2014 - National Acad Sciences
Cancer-associated inflammation mobilizes a variety of leukocyte populations that can inhibit
or enhance tumor cell growth in situ. These subsets include γδ T cells, which can infiltrate …

[HTML][HTML] Fatty acid metabolism in ovarian cancer: Therapeutic implications

H Yoon, S Lee - International Journal of Molecular Sciences, 2022 - mdpi.com
Ovarian cancer is the most malignant gynecological tumor. Previous studies have reported
that metabolic alterations resulting from deregulated lipid metabolism promote ovarian …

[HTML][HTML] The crowded crosstalk between cancer cells and stromal microenvironment in gynecological malignancies: biological pathways and therapeutic implication

R De Nola, A Menga, A Castegna, V Loizzi… - International journal of …, 2019 - mdpi.com
The tumor microenvironment plays a pillar role in the progression and the distance
dissemination of cancer cells in the main malignancies affecting women—epithelial ovarian …

[HTML][HTML] Prognostic and predictive role of tumor-infiltrating lymphocytes (TILs) in ovarian cancer

D Fanale, A Dimino, E Pedone, C Brando, LR Corsini… - Cancers, 2022 - mdpi.com
Simple Summary In this review, we present current knowledge about the prognostic and
predictive role of tumor-infiltrating lymphocytes (TILs) in ovarian cancer since this tumor …