[HTML][HTML] Tissue damage and oxidant/antioxidant balance

A Kisaoglu, B Borekci, OE Yapca, H Bilen… - The Eurasian journal …, 2013 - ncbi.nlm.nih.gov
The oxidant/antioxidant balance in healthy tissues is maintained with a predominance of
antioxidants. Various factors that can lead to tissue damage disrupt the oxidant/antioxidant …

Oxidative stress implications in the affective disorders: main biomarkers, animal models relevance, genetic perspectives, and antioxidant approaches

IM Balmus, A Ciobica, I Antioch… - … medicine and cellular …, 2016 - Wiley Online Library
The correlation between the affective disorders and the almost ubiquitous pathological
oxidative stress can be described in a multifactorial way, as an important mechanism of …

The relevance of oxidative stress status in first episode and recurrent depression

C Stefanescu, A Ciobica - Journal of affective disorders, 2012 - Elsevier
Oxidative and nitrosative stress (O&NS) could play an important role in the pathophysiology
of major depression (MDD). The aim of the present work was to evaluate the specific activity …

Pharmacological update of mirtazapine: a narrative literature review

EHM Hassanein, HS Althagafy, MA Baraka… - Naunyn-schmiedeberg's …, 2024 - Springer
Mirtazapine (MTZ) is an antidepressant drug with an exceptional pharmacological profile. It
also has an excellent safety and tolerability profile. The present review provides a …

[HTML][HTML] Protective effects of vitamin D on ischemia-reperfusion injury of the ovary in a rat model

VY Tokgoz, M Sipahi, O Keskin… - Iranian journal of basic …, 2018 - ncbi.nlm.nih.gov
Objective (s): The aim of the present study is to investigate probable acute effects of vitamin
D on ischemia-reperfusion injury in the rat ovary. Materials and Methods: A group of 30 …

Protective effect of mirtazapine against acetic acid-induced ulcerative colitis in rats: role of NLRP3 inflammasome pathway

HM Hafez, MA Ibrahim, WY Abdelzaher, AA Gad… - International …, 2021 - Elsevier
Aims Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that causes long-lasting
inflammation on the innermost lining of the colon and rectum. Mirtazapine (MRT) is a well …

Differential effects of selective serotonin reuptake inhibitors on paraoxonase-1 enzyme activity: An in vitro study

Y Demir, N Balcı, M Gürbüz - … and physiology part C: toxicology & …, 2019 - Elsevier
Abstract Paraoxonase-I (PON1) is a calcium-dependent hydrolytic enzyme, plays an
important role in most antioxidant properties related to high-density lipoprotein (HDL) …

Mirtazapine protects against cisplatin‐induced oxidative stress and DNA damage in the rat brain

M Gulec, E Oral, OB Dursun, A Yucel… - Psychiatry and …, 2013 - Wiley Online Library
Aim Cisplatin chemotherapy is associated with neurotoxicity, and oxidative stress might play
an important role in the pathogenesis. Mirtazapine may be a preventative agent via its less …

Protective effects of mirtazapine and chrysin on experimentally induced testicular damage in rats

AE El-Sisi, ME El-Sayad, NM Abdelsalam - Biomedicine & …, 2017 - Elsevier
Mirtazapine is an antidepressant with prominent antioxidant effects. Chrysin, a natural
flavone, exhibits multiple pharmacological actions. This study was designed to investigate …

Protective effect of infliximab on ischemia/reperfusion-induced damage in rat kidney

C Tasdemir, S Tasdemir, N Vardi, B Ates… - Renal failure, 2012 - Taylor & Francis
Objective: To investigate the protective effect of infliximab on ischemia–reperfusion (I/R)
injury of the rat kidney. Methods: Twenty-eight male Wistar albino rats were divided into four …