Anticancer activity of palladium-based complexes against triple-negative breast cancer
M Vojtek, MPM Marques, IM Ferreira, H Mota-Filipe… - Drug Discovery …, 2019 - Elsevier
Highlights•TNBC is an unmet medical need with poor survival rates and no targeted
therapy.•TNBC resists conventional chemotherapy and surgical strategies.•A review of 121 …
therapy.•TNBC resists conventional chemotherapy and surgical strategies.•A review of 121 …
Review of comparative studies of cytotoxic activities of Pt (II), Pd (II), Ru (II)/(III) and Au (III) complexes, their kinetics of ligand substitution reactions and DNA/BSA …
New concepts and various strategies are being explored to improve the cytotoxicity of metal-
based complexes. One of those strategies is to fine-tune the substitution kinetics of metallo …
based complexes. One of those strategies is to fine-tune the substitution kinetics of metallo …
Synthesis, characterization, DNA/BSA interactions and in vitro cytotoxicity study of palladium (II) complexes of hispolon derivatives
X Wei, Y Yang, J Ge, X Lin, D Liu, S Wang… - Journal of inorganic …, 2020 - Elsevier
Thirteen novel palladium (II) complexes of the general formula [Pd (bipy)(O, O′-dkt)](PF
6),(where bipy is 2, 2′-bipyridine and O, O′-dkt is β-diketonate ligand hispolon or its …
6),(where bipy is 2, 2′-bipyridine and O, O′-dkt is β-diketonate ligand hispolon or its …
In vitro cytotoxicity evaluation of organotin (IV) complexes derived from bisphosphoramide ligand: DNA binding and molecular docking studies
Considering the valuable position of organotins and the biotic role of phosphorus
compounds in biological processes, in this research work, we investigated and introduced a …
compounds in biological processes, in this research work, we investigated and introduced a …
New monofunctional platinum (II) and palladium (II) complexes: Studies of the nucleophilic substitution reactions, DNA/BSA interaction, and cytotoxic activity
D Ćoćić, S Jovanović, S Radisavljević… - Journal of Inorganic …, 2018 - Elsevier
Four new complexes [Pd (H 2 L tBu) Cl] Cl (Pd1),[Pt (H 2 L tBu) Cl] Cl (Pt1),[Pd (Me 2 L tBu)
Cl] Cl (Pd2) and [Pt (Me 2 L tBu) Cl] Cl (Pt2)(where H 2 L tBu= 2, 6-bis (5-(tert-butyl)-1H …
Cl] Cl (Pd2) and [Pt (Me 2 L tBu) Cl] Cl (Pt2)(where H 2 L tBu= 2, 6-bis (5-(tert-butyl)-1H …
Synthesis and structure of a new thiazoline-based palladium (II) complex that promotes cytotoxicity and apoptosis of human promyelocytic leukemia HL-60 cells
Cisplatin is one of the most widely used chemotherapeutic agents in the treatment of
different tumors but has high toxicity and side effects. Therefore, the synthesis of new …
different tumors but has high toxicity and side effects. Therefore, the synthesis of new …
In vitro and in vivo effect of palladacycles: targeting A2780 ovarian carcinoma cells and modulation of angiogenesis
F Reigosa-Chamorro, LR Raposo… - Inorganic …, 2021 - ACS Publications
Palladacycles are versatile organometallic compounds that show potential for therapeutic
use. Here are described the synthesis and characterization of mono-and dinuclear …
use. Here are described the synthesis and characterization of mono-and dinuclear …
New dinuclear palladium (II) complexes with benzodiazines as bridging ligands: interactions with CT-DNA and BSA, and cytotoxic activity
AA Franich, MD Živković, D Ćoćić, B Petrović… - JBIC Journal of …, 2019 - Springer
Three new dinuclear Pd (II) complexes with general formula [{Pd (en) Cl} 2 (μ-L)](NO 3) 2 [L
is bridging ligand quinoxaline (Pd1), quinazoline (Pd2) and phthalazine (Pd3)] were …
is bridging ligand quinoxaline (Pd1), quinazoline (Pd2) and phthalazine (Pd3)] were …
Homo-and hetero-dinuclear Pt (II)/Pd (II) complexes: Studies of hydrolysis, nucleophilic substitution reactions, DNA/BSA interactions, DFT calculations, molecular …
D Ćoćić, S Jovanović-Stević, R Jelić, S Matić… - Dalton …, 2020 - pubs.rsc.org
Three dinuclear complexes [Pd2 (tpbd) Cl2] Cl2 (PP1),[Pt2 (tpbd) Cl2] Cl2 (PP2) and [PdPt
(tpbd) Cl2] Cl2 (PP3)(tpbd= N, N, N′, N′-tetrakis (2-pyridylmethyl) benzene-1, 4-diamine) …
(tpbd) Cl2] Cl2 (PP3)(tpbd= N, N, N′, N′-tetrakis (2-pyridylmethyl) benzene-1, 4-diamine) …
New gold pincer-type complexes: synthesis, characterization, DNA binding studies and cytotoxicity
S Radisavljević, I Bratsos, A Scheurer… - Dalton …, 2018 - pubs.rsc.org
With the aim of assessing whether Au (III) compounds with pincer type ligands might be
utilized as potential antitumor agents, three new monofunctional Au (III) complexes of the …
utilized as potential antitumor agents, three new monofunctional Au (III) complexes of the …