Synthetic application of asymmetric catalysis relies on strategic alignment of bond
construction to creation of chirality of a target molecule. Remote desymmetrization offers …

Catalytic asymmetric conjugate additions of carbon nucleophiles have emerged as a potent
tool for constructing multi-stereogenic molecules with precise stereochemical control. This …

Herein, we describe the convergent enantioselective total synthesis of himalensine A in 18
steps, enabled by a highly enantio-and diastereoselective construction of the morphan core …

The amino groups of thio‐and selenoamides can act as stronger hydrogen‐bond donors
than of carboxamides, despite the lower electronegativity of S and Se. This phenomenon …

The bicyclo [3.3. 1] nonane ring represents an attractive yet challenging synthetic targets in
the field of organic synthesis, especially in a stereocontrolled fashion. Over the past two …

Herein we report the first enantioselective total synthesis of (+)‐incargranine A, in nine steps.
The total synthesis was enabled by an enantioselective intramolecular organocatalysed …

Deselenization of 1, 2-diselenides offers a promising tool for the construction of
organochalcogenides. However, the requirement of transition metals and harsh reaction …

A divergent asymmetric synthetic route to (−)-alloaristoteline and (+)-aristoteline is
described. The key doubly bridged tricyclic enol triflate common intermediate prepared via …

The development of reliable approaches to construct enantioenriched cyclic ketones
bearing multiple stereocenters has attracted intense interest in synthetic chemistry, yet …

Quaternary stereogenic centers are of great importance because of their prevalence in a
series of bioactive natural products and pharmaceuticals. Although the catalytic asymmetric …