[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

Q Zhu, Z Chen, PK Paul, Y Lu, W Wu, J Qi - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …

[HTML][HTML] Adapting liposomes for oral drug delivery

H He, Y Lu, J Qi, Q Zhu, Z Chen, W Wu - Acta pharmaceutica sinica B, 2019 - Elsevier
Liposomes mimic natural cell membranes and have long been investigated as drug carriers
due to excellent entrapment capacity, biocompatibility and safety. Despite the success of …

Bilosomes as promising nanovesicular carriers for improved transdermal delivery: construction, in vitro optimization, ex vivo permeation and in vivo evaluation

S Ahmed, MA Kassem, S Sayed - International Journal of …, 2020 - Taylor & Francis
Purpose The goal of this research was to enhance the transdermal delivery of lornoxicam
(LX), using nanovesicular carriers composed of the bile salt sodium deoxycholate (SDC) …

Current approaches in lipid-based nanocarriers for oral drug delivery

M Plaza-Oliver, MJ Santander-Ortega… - Drug Delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Encapsulation, protection, and release of hydrophilic active components: Potential and limitations of colloidal delivery systems

DJ McClements - Advances in colloid and interface science, 2015 - Elsevier
There have been major advances in the development of edible colloidal delivery systems for
hydrophobic bioactives in recent years. However, there are still many challenges associated …

Micro and nanoscale technologies in oral drug delivery

S Ahadian, JA Finbloom, M Mofidfar, SE Diltemiz… - Advanced drug delivery …, 2020 - Elsevier
Oral administration is a pillar of the pharmaceutical industry and yet it remains challenging to
administer hydrophilic therapeutics by the oral route. Smart and controlled oral drug delivery …

[图书][B] Nanoparticle-and microparticle-based delivery systems: Encapsulation, protection and release of active compounds

DJ McClements - 2014 - books.google.com
This book covers the formation, properties, characterization, and application of different
kinds of colloidal delivery systems that can be utilized within the food industry, including …

Emerging micro-and nanotechnology based synthetic approaches for insulin delivery

R Mo, T Jiang, J Di, W Tai, Z Gu - Chemical society reviews, 2014 - pubs.rsc.org
Insulin is essential for type 1 and advanced type 2 diabetics to maintain blood glucose levels
and prolong lives. The traditional administration requires frequent subcutaneous insulin …

Spray-drying encapsulation of protein hydrolysates and bioactive peptides: Opportunities and challenges

K Sarabandi, P Gharehbeglou, SM Jafari - Drying Technology, 2020 - Taylor & Francis
In the recent years, extensive research is under way about the use of natural bioactive
compounds and production of functional foods to increase community health and reduce the …