As early as the 19th century, OIH was observed in patients receiving morphine for pain. It
was recognized that a potent analgesic such as morphine could actually result in an …

Flip-flop pharmacokinetics is a phenomenon often encountered with extravascularly
administered drugs. Occurrence of flip-flop spans preclinical to human studies. The purpose …

Background: Comprehensive, evidence-based guidelines for interventional techniques in
the management of chronic spinal pain are described here to provide recommendations for …

Background: Chronic persistent pain as a result of terminal illness, either as a consequence
of the disease or the necessary treatment, is common in patients with cancer. For these …

Objective: To determine the clinical effectiveness of therapeutic lumbar facet joint nerve
blocks with or without steroids in managing chronic low back pain of facet joint origin …

Pain Physician: March/April 2011; 14: 123-143 124 www. painphysicianjournal. com
patterns of drug use and compliance so as to direct the type and conduct of treatment that …

Background: Intrathecal drug infusion therapy is usually considered when spinal-acting
analgesics or antispasmodics administered via the oral or transdermal routes fail to control …

Background: Epidural steroid injection is the most frequently performed pain procedure. This
study of epidural steroid “control” injections aimed to determine whether epidural nonsteroid …

E36 www. painphysicianjournal. com broken system and have done little to address the
underlying problems: its unsustainable finances and threat to our nation's future. Rather than …

Background: Variation in the intensity of neurostimulation due to body position is a practical
problem for many patients implanted with spinal cord stimulation (SCS) systems because …