Cdk5-dependent phosphorylation of CaV3. 2 T-type channels: possible role in nerve ligation-induced neuropathic allodynia and the compound action potential in …
K Gomez, A Calderón-Rivera, A Sandoval… - Journal of …, 2020 - Soc Neuroscience
Voltage-gated T-type Ca2+ (CaV3) channels regulate diverse physiological events,
including neuronal excitability, and have been linked to several pathological conditions such …
including neuronal excitability, and have been linked to several pathological conditions such …
Contemporary enzyme-based methods for recombinant proteins in vitro phosphorylation
M Slovakova, Z Bilkova - Catalysts, 2021 - mdpi.com
Phosphorylation is a reversible, enzyme-controlled posttranslational process affecting
approximately one-third of all proteins in eukaryotic cells at any given time. Any deviation in …
approximately one-third of all proteins in eukaryotic cells at any given time. Any deviation in …
Development of KVO treatment strategies for chronic pain in a rat model of Gulf War Illness
LK Flunker, TJ Nutter, CM Bowers… - Toxicology and Applied …, 2022 - Elsevier
We examined whether combinations of K v 7 channel openers could be effective modifiers of
deep tissue nociceptor activity; and whether such combinations could then be optimized for …
deep tissue nociceptor activity; and whether such combinations could then be optimized for …
Structural determinants of Kv7. 5 potassium channels that confer changes in phosphatidylinositol 4, 5-bisphosphate (PIP2) affinity and signaling sensitivities in smooth …
LI Brueggemann, LL Cribbs, KL Byron - Molecular Pharmacology, 2020 - ASPET
Smooth muscle cells express Kv7. 4 and Kv7. 5 voltage-dependent potassium channels,
which have each been implicated as regulators of smooth muscle contractility, though they …
which have each been implicated as regulators of smooth muscle contractility, though they …
Optimizing Kv7 Openers for Treatment of GWI Pain
BY Cooper, FLORIDA UNIV GAINESVILLE - 2021 - apps.dtic.mil
Our laboratory developed an animal model that replicates some of the symptoms of the
chronic pain of GWI. Through this animal model we identified molecular targets in pain …
chronic pain of GWI. Through this animal model we identified molecular targets in pain …
[PDF][PDF] Contemporary Enzyme-Based Methods for Recombinant Proteins In Vitro Phosphorylation. Catalysts 2021, 11, 1007
M Slovakova, Z Bilkova - catalysts, 2021 - mdpi.com
Phosphorylation is a reversible, enzyme-controlled posttranslational process affecting
approximately one-third of all proteins in eukaryotic cells at any given time. Any deviation in …
approximately one-third of all proteins in eukaryotic cells at any given time. Any deviation in …