Immunomodulatory effects of mesenchymal stem cells in peripheral nerve injury

X Li, Y Guan, C Li, T Zhang, F Meng, J Zhang… - Stem Cell Research & …, 2022 - Springer
Various immune cells and cytokines are present in the aftermath of peripheral nerve injuries
(PNI), and coordination of the local inflammatory response is of great significance for the …

Stem‐cell–based therapies to enhance peripheral nerve regeneration

CA Kubiak, J Grochmal, TA Kung, PS Cederna… - Muscle & …, 2020 - Wiley Online Library
Peripheral nerve injury remains a major cause of morbidity in trauma patients. Despite
advances in microsurgical techniques and improved understanding of nerve regeneration …

Application of dental pulp stem cells for bone and neural tissue regeneration in oral and maxillofacial region

Y Fujii, A Hatori, D Chikazu… - Stem Cells …, 2023 - Wiley Online Library
In the oral and maxillofacial region, the treatment of severe bone defects, caused by
fractures, cancers, congenital abnormalities, etc., remains a great challenge. In addition …

FGF10 Enhances Peripheral Nerve Regeneration via the Preactivation of the PI3K/Akt Signaling-Mediated Antioxidant Response

L Dong, R Li, D Li, B Wang, Y Lu, P Li, F Yu… - Frontiers in …, 2019 - frontiersin.org
The process of axonal regeneration after peripheral nerve injury (PNI) is slow and mostly
incomplete. Previous studies have investigated the neuroprotective effects of fibroblast …

Epigenetic regulation of dental pulp stem cell fate

D Zhou, L Gan, Y Peng, Y Zhou, X Zhou… - Stem Cells …, 2020 - Wiley Online Library
Epigenetic regulation, mainly involving DNA methylation, histone modification, and
noncoding RNAs, affects gene expression without modifying the primary DNA sequence and …

Development of alginate-spermidine micro/nanogels as potential antioxidant and anti-inflammatory tool in peripheral nerve injuries. Formulation studies and physico …

C Valentino, B Vigani, I Fedeli, D Miele… - International Journal of …, 2022 - Elsevier
The development of a successful strategy to ensure a full recovery in patients affected by
peripheral nerve injury (PNI), one of the most debilitating pathologies, is, still today, a major …

The influence of reduced graphene oxide on stem cells: a perspective in peripheral nerve regeneration

X Yao, Z Yan, X Wang, H Jiang, Y Qian… - Regenerative …, 2021 - academic.oup.com
Graphene and its derivatives are fascinating materials for their extraordinary electrochemical
and mechanical properties. In recent decades, many researchers explored their applications …

Anti-inflammatory effect of dental pulp stem cells

FY Li, XX Wang, J Shi, ST Wu, WB Xing… - Frontiers in …, 2023 - frontiersin.org
Dental pulp stem cells (DPSCs) have received a lot of attention as a regenerative medicine
tool with strong immunomodulatory capabilities. The excessive inflammatory response …

Development and validation of clinically Mimicable model of frostbite injury-induced chronic pain

O Ummadisetty, A Gadepalli, D Chouhan, V Tiwari - Cellular Signalling, 2024 - Elsevier
Frostbite, a debilitating condition, significantly affects the well-being of military veterans and
high-altitude residents, causing severe clinical complications such as chronic pain that …

Phytohormone abscisic acid ameliorates neuropathic pain via regulating LANCL2 protein abundance and glial activation at the spinal cord

DW Maixner, D Christy, L Kong… - Molecular …, 2022 - journals.sagepub.com
Spinal neuroinflammation plays a critical role in the genesis of neuropathic pain.
Accumulating data suggest that abscisic acid (ABA), a phytohormone, regulates …