血管内皮细胞和内皮细胞释放的活性因子是调控血管舒张功能的重要因素. 糖尿病是慢性心血管
疾病的高危因素之一. 目前认为高糖和糖尿病引起的内皮细胞功能障碍是造成血管功能改变 …

Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

The endothelial angiopoietin (ANG)–TIE growth factor receptor pathway regulates vascular
permeability and pathological vascular remodelling during inflammation, tumour …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

The ang opoietin/t yrosine kinase with i mmunoglobulin and e pidermal growth factor
homology domains (Ang/Tie) pathway is an emerging key regulator in vascular development …

Many central nervous system diseases currently lack effective treatment and are often
associated with defects in microvascular function, including a failure to match the energy …

Purpose The phase 2 BOULEVARD trial compared safety and efficacy of faricimab, a novel
bispecific antibody targeting angiopoietin-2 and vascular endothelial growth factor-A (VEGF …

This review summarizes the latest findings in the literature of Angiopoietin-2 (Ang-2),
Tyrosine-protein kinase receptor (Tie-2) complex, and faricimab along with their involvement …

Anti‐angiogenic therapies using biological molecules that neutralize vascular endothelial
growth factor‐A (VEGF‐A) have revolutionized treatment of retinal vascular diseases …

The angiopoietin/Tie (ANG/Tie) receptor system controls developmental and tumor
angiogenesis, inflammatory vascular remodeling, and vessel leakage. ANG1 is a Tie2 …