Sex differences in COVID-19: the role of androgens in disease severity and progression
Abstract Purpose Throughout the SARS-CoV2 pandemic, multiple reports show higher
percentages of hospitalization, morbidity, and mortality among men than women, indicating …
percentages of hospitalization, morbidity, and mortality among men than women, indicating …
[HTML][HTML] Sex differences in immune responses
SL Klein, KL Flanagan - Nature Reviews Immunology, 2016 - nature.com
Males and females differ in their immunological responses to foreign and self-antigens and
show distinctions in innate and adaptive immune responses. Certain immunological sex …
show distinctions in innate and adaptive immune responses. Certain immunological sex …
[HTML][HTML] The relationship between circulating testosterone and inflammatory cytokines in men
NV Mohamad, SK Wong, WNW Hasan, JJ Jolly… - The Aging …, 2018 - Taylor & Francis
Testosterone is the predominant gonadal androgen in men. Low testosterone levels are
found to be associated with an increased in metabolic risk and systematic inflammation …
found to be associated with an increased in metabolic risk and systematic inflammation …
The anti-inflammatory effects of testosterone
VE Bianchi - Journal of the endocrine society, 2019 - academic.oup.com
Low plasma testosterone (T) levels correlated with metabolic syndrome, cardiovascular
diseases, and increased mortality risk. T exerts a significant effect on the regulation of …
diseases, and increased mortality risk. T exerts a significant effect on the regulation of …
Adipose tissue dysfunction and obesity-related male hypogonadism
VA Genchi, E Rossi, C Lauriola, R D'Oria… - International Journal of …, 2022 - mdpi.com
Obesity is a chronic illness associated with several metabolic derangements and
comorbidities (ie, insulin resistance, leptin resistance, diabetes, etc.) and often leads to …
comorbidities (ie, insulin resistance, leptin resistance, diabetes, etc.) and often leads to …
Why does COVID‐19 kill more elderly men than women? Is there a role for testosterone?
V Papadopoulos, L Li, M Samplaski - Andrology, 2021 - Wiley Online Library
Background Recent epidemiological data indicate that there may be a gender predisposition
to COVID‐19, with men predisposed to being most severely affected, and older men …
to COVID‐19, with men predisposed to being most severely affected, and older men …
[HTML][HTML] Covid-19 kills more men than women: an overview of possible reasons
A Capuano, F Rossi, G Paolisso - Frontiers in cardiovascular …, 2020 - frontiersin.org
The high mortality observed in Covid-19 patients may be related to unrecognized pulmonary
embolism, pulmonary thrombosis, or other underlying cardiovascular diseases. Recent data …
embolism, pulmonary thrombosis, or other underlying cardiovascular diseases. Recent data …
[HTML][HTML] Sex-dependent outcome of hepatitis B and C viruses infections: synergy of sex hormones and immune responses?
A Ruggieri, MC Gagliardi, S Anticoli - Frontiers in Immunology, 2018 - frontiersin.org
Hepatitis B virus (HBV) and hepatitis C virus (HCV) are hepatotropic viruses that differ in
their genomic content, life cycle and molecular prognosis. HBV and HCV establish chronic …
their genomic content, life cycle and molecular prognosis. HBV and HCV establish chronic …
[HTML][HTML] Molecular and biological mechanisms underlying gender differences in COVID-19 severity and mortality
Z Wehbe, SH Hammoud, HM Yassine… - Frontiers in …, 2021 - frontiersin.org
Globally, over two million people have perished due to the recent pandemic caused by
SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher …
SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher …
The immune response to COVID‐19: Does sex matter?
Abstract The coronavirus disease 2019 (COVID‐19) pandemic has created unprecedented
challenges worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
challenges worldwide. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …