Promising natural products in new drug design, development, and therapy for skin disorders: An overview of scientific evidence and understanding their mechanism of …

NA Mohd Zaid, M Sekar, SR Bonam… - Drug design …, 2023 - Taylor & Francis
The skin is the largest organ in the human body, composed of the epidermis and the dermis.
It provides protection and acts as a barrier against external menaces like allergens …

[HTML][HTML] Advance and challenges in the treatment of skin diseases with the transdermal drug delivery system

T Cheng, Z Tai, M Shen, Y Li, J Yu, J Wang, Q Zhu… - Pharmaceutics, 2023 - mdpi.com
Skin diseases are among the most prevalent non-fatal conditions worldwide. The
transdermal drug delivery system (TDDS) has emerged as a promising approach for treating …

Revisiting techniques to evaluate drug permeation through skin

VK Rapalli, A Mahmood, T Waghule… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Investigating the transportation of a drug molecule through various layers of skin
and determining the amount of drug retention in skin layers is of prime importance in …

A comprehensive review of the pharmacological importance of dietary flavonoids as hepatoprotective agents

Gajender, A Mazumder, A Sharma… - Evidence‐Based …, 2023 - Wiley Online Library
The liver is a crucial organ that is involved in various kinds of metabolic activity and a very
stable accessory gland for the digestive system. Long‐term or persistent inflammation and …

[HTML][HTML] Advances in the application of natural products and the novel drug delivery systems for psoriasis

J Xie, S Huang, H Huang, X Deng, P Yue… - Frontiers in …, 2021 - frontiersin.org
Psoriasis, an incurable autoimmune skin disease, is one of the most common immune-
mediated disorders. Presently, numerous clinical research studies are underway, and …

[HTML][HTML] Flavonoids present in propolis in the battle against photoaging and psoriasis

CR Rivera-Yañez, PA Ruiz-Hurtado… - Antioxidants, 2021 - mdpi.com
The skin is the main external organ. It protects against different types of potentially harmful
agents, such as pathogens, or physical factors, such as radiation. Skin disorders are very …

Natural alternatives targeting psoriasis pathology and key signaling pathways: A focus on phytochemicals

IK Koycheva, AS Marchev, ID Stoykova… - Phytochemistry …, 2023 - Springer
Psoriasis is an autoimmune, chronic skin disorder with complex and yet unclear
pathogenesis. It is associated with many conditions, including psoriatic arthritis …

[HTML][HTML] Lipid-based nanoformulation optimization for achieving cutaneous targeting: Niosomes as the potential candidates to fulfill this aim

YK Lin, CY Hsiao, A Alshetaili, IA Aljuffali… - European journal of …, 2023 - Elsevier
The present study screened the utility of topically-applied nanoformulations to target the
drugs/actives into the skin reservoir with the reduction of possible systemic absorption. The …

[HTML][HTML] Phytoestrogen β-Sitosterol Exhibits Potent In Vitro Antiviral Activity against Influenza A Viruses

S Shokry, A Hegazy, AM Abbas, I Mostafa, IH Eissa… - Vaccines, 2023 - mdpi.com
Influenza is a contagious infection in humans that is caused frequently by low pathogenic
seasonal influenza viruses and occasionally by pathogenic avian influenza viruses (AIV) of …

Preclinical study models of psoriasis: State-of-the-art techniques for testing pharmaceutical products in animal and nonanimal models

K Yadav, D Singh, MR Singh, S Minz… - International …, 2023 - Elsevier
Local and systemic treatments exist for psoriasis, but none can do more than control its
symptoms because of its numerous unknown mechanisms. The lack of validated testing …