Conspectus Metals are partners for an estimated one-third of the proteome and vary in
complexity from mononuclear centers to organometallic cofactors. Vitamin B12 or cobalamin …

Abstract Vitamin B12 (cobalamin, Cbl) is required as a cofactor by two human enzymes, 5‐
methyltetrahydrofolate‐homocysteine methyltransferase (MTR) and methylmalonyl‐CoA …

Oxygen reduction reaction (ORR) is the bottleneck of metal‐air batteries and fuel cells.
Strain regulation can change the geometry and adjust the surface charge distribution of …

Abstract Development of a versatile, sustainable and efficient photosynthesis system that
integrates intricate catalytic networks and energy modules at the same location is of …

The biologically important amino acid homocysteine links sulfur, methionine, and one-
carbon metabolism. This review describes its initial discovery, the identification of the clinical …

The Bol2 homolog Fra2 and monothiol glutaredoxin Grx4 together play essential roles in
regulating iron homeostasis in Schizosaccharomyces pombe. In vivo studies indicate that …

Nuclear factor erythroid 2-related factor 2 (Nrf2) promotes expression of a large number of
antioxidant genes and multiple studies have described oxidative stress and impaired …

Photoinduced ligand-to-metal charge transfer (LMCT) is a powerful technique for the
formation of reactive radical species via homolytic cleavage of the metal–ligand bond. Here …

Combining abiotic photocatalytic modules with enzymatic conversion to reform biomass
represents a compelling way for sustainable energy schemes but faces marked challenges …

Many naturally occurring metalloenzymes are gated by rate-limiting conformational
changes, and there exists a critical interplay between macroscopic structural …