[HTML][HTML] Classical renin-angiotensin system in kidney physiology
MA Sparks, SD Crowley, SB Gurley… - Comprehensive …, 2014 - ncbi.nlm.nih.gov
The renin-angiotensin system has powerful effects in control of the blood pressure and
sodium homeostasis. These actions are coordinated through integrated actions in the …
sodium homeostasis. These actions are coordinated through integrated actions in the …
Food‐originating ACE inhibitors, including antihypertensive peptides, as preventive food components in blood pressure reduction
A Iwaniak, P Minkiewicz… - … Reviews in Food Science …, 2014 - Wiley Online Library
This work is a literature overview on angiotensin‐converting enzyme (ACE) inhibitory/
antihypertensive peptides in food protein sources. The following aspects related to peptides …
antihypertensive peptides in food protein sources. The following aspects related to peptides …
[HTML][HTML] Tumor necrosis factor-α convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) …
DW Lambert, M Yarski, FJ Warner, P Thornhill… - Journal of Biological …, 2005 - ASBMB
Angiotensin-converting enzyme-2 (ACE2) is a critical regulator of heart function and a
cellular receptor for the causative agent of severe-acute respiratory syndrome (SARS) …
cellular receptor for the causative agent of severe-acute respiratory syndrome (SARS) …
[HTML][HTML] Hypotensive peptides from milk proteins
RJ FitzGerald, BA Murray, DJ Walsh - The Journal of nutrition, 2004 - Elsevier
Hypertension is the major controllable risk factor associated with cardiovascular disease
(CVD) events such as myocardial infarction, stroke, heart failure, and end-stage diabetes. A …
(CVD) events such as myocardial infarction, stroke, heart failure, and end-stage diabetes. A …
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production
BA Murray, RJ FitzGerald - Current pharmaceutical design, 2007 - ingentaconnect.com
Food proteins contain latent biofunctional peptide sequences within their primary structures
which may have the ability to exert a physiological response in vivo. A large range of …
which may have the ability to exert a physiological response in vivo. A large range of …
[HTML][HTML] Amyloid β-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor
ML Hemming, DJ Selkoe - Journal of Biological Chemistry, 2005 - ASBMB
Human genetic data have associated angiotensin-converting enzyme (ACE) with Alzheimer
disease (AD), and purified ACE has been reported to cleave synthetic amyloid β-protein (Aβ) …
disease (AD), and purified ACE has been reported to cleave synthetic amyloid β-protein (Aβ) …
Membrane protein secretases
NM Hooper, EH KARRAN, AJ TURNER - Biochemical Journal, 1997 - portlandpress.com
A diverse range of membrane proteins of Type I or Type II topology also occur as a
circulating, soluble form. These soluble forms are often derived from the membrane form by …
circulating, soluble form. These soluble forms are often derived from the membrane form by …
[HTML][HTML] The Hemoregulatory Peptide N-Acetyl-Ser-Asp-Lys-Pro Is a Natural and Specific Substrate of the N-terminal Active Site of Human Angiotensin-converting …
A Rousseau, A Michaud, MT Chauvet, M Lenfant… - Journal of Biological …, 1995 - ASBMB
Angiotensin I-converting enzyme (ACE) is a zinc-dipeptidyl carboxypeptidase, which
contains two similar domains, each possessing a functional active site. Respective …
contains two similar domains, each possessing a functional active site. Respective …
The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice.
CR Esther, EM Marino, TE Howard… - The Journal of …, 1997 - Am Soc Clin Investig
Angiotensin-converting enzyme (ACE) generates the vasoconstrictor angiotensin II, which
plays a critical role in maintenance of blood pressure in mammals. Although significant ACE …
plays a critical role in maintenance of blood pressure in mammals. Although significant ACE …
[18] Peptidyl dipeptidase A: Angiotensin I-converting enzyme
P Corvol, TA Williams, F Soubrier - Methods in enzymology, 1995 - Elsevier
Peptidyl dipeptidase A (EC 3.4. 15.1) is a Zn2+-metallopeptidase which acts on many
substrates, primarily by releasing a C-terminal dipeptide. Its broad substrate specificity …
substrates, primarily by releasing a C-terminal dipeptide. Its broad substrate specificity …