The renin-angiotensin system has powerful effects in control of the blood pressure and
sodium homeostasis. These actions are coordinated through integrated actions in the …

This work is a literature overview on angiotensin‐converting enzyme (ACE) inhibitory/
antihypertensive peptides in food protein sources. The following aspects related to peptides …

Angiotensin-converting enzyme-2 (ACE2) is a critical regulator of heart function and a
cellular receptor for the causative agent of severe-acute respiratory syndrome (SARS) …

Hypertension is the major controllable risk factor associated with cardiovascular disease
(CVD) events such as myocardial infarction, stroke, heart failure, and end-stage diabetes. A …

Food proteins contain latent biofunctional peptide sequences within their primary structures
which may have the ability to exert a physiological response in vivo. A large range of …

Human genetic data have associated angiotensin-converting enzyme (ACE) with Alzheimer
disease (AD), and purified ACE has been reported to cleave synthetic amyloid β-protein (Aβ) …

A diverse range of membrane proteins of Type I or Type II topology also occur as a
circulating, soluble form. These soluble forms are often derived from the membrane form by …

Angiotensin I-converting enzyme (ACE) is a zinc-dipeptidyl carboxypeptidase, which
contains two similar domains, each possessing a functional active site. Respective …

Angiotensin-converting enzyme (ACE) generates the vasoconstrictor angiotensin II, which
plays a critical role in maintenance of blood pressure in mammals. Although significant ACE …

Peptidyl dipeptidase A (EC 3.4. 15.1) is a Zn2+-metallopeptidase which acts on many
substrates, primarily by releasing a C-terminal dipeptide. Its broad substrate specificity …