The antimalarial activity of chloroquine-pyrazole analogues, synthesized from the reaction of
1, 1, 1-trifluoro-4-methoxy-3-alken-2-ones with 4-hydrazino-7-chloroquinoline, has been …

Previously published information regarding this heterocyclic system can be found in
Houben±Weyl, Vol. 13/6, pp 181±522 and Vol. 22b, pp 1508±1516. Pyrazole (1, 2-diazole) …

The regiospecific synthesis and structural elucidation by NMR spectroscopy, AM1
semiempirical MO calculations and X-ray diffraction of a novel series of twelve 3-aryl [alkyl]-5 …

The synthesis of 3-aryl [alkyl]-5-hydroxy-5-trifluoromethyl-4, 5-dihydro-1H-1-
pyrazolethiocarboxyamides (2a–g) from the direct cyclo-condensation reaction of β …

A convenient method for the preparation of 5-hydroxy-5-trihalo-4, 5-dihydroisoxazoles and β-
enamino trihalomethyl ketones, from the reaction of 1, 1, 1-trihalo-4-alkoxy-3-alken-2-ones …

A series of twelve 5-bromo [5, 5-dibromo]-4-methoxy-1, 1, 1-trihalo-3-alken-2-ones 5a-d, 6a-
d, 7a, 9a, 10a and 6-bromo-5-methoxy-1, 1, 1, 2, 2-pentafluoro-4-hexen-2-one (8a) were …

The synthesis of a series of 5‐and 6‐substituted 4‐trihalomethyl‐2‐methylthiopyrimidines,
prepared from the cyclocondensation reaction of β‐alkoxyvinyl tri [fluoro] chloromethyl …

Abstract The synthesis of 4‐trifluoromethyl‐2‐methyl [phenyl] pyrimidines and the
corresponding tetrahydro derivatives from the cyclo‐condensation reaction of β‐alkoxyvinyl …

This work reports a successful synthesis of two new series of 2-(aryl/heteroaryl)-6-
(morpholin-4-yl/pyrrolidin-1-yl)-(4-trifluoromethyl) quinolines via the Buchwald–Hartwig …

The synthesis and structural elucidation of a new series of six 6-amino-2-alkyl
(aryl/heteroaryl)-4-(trifluoromethyl) quinolines are reported, yielding 22 to 87% isolated …