Advances in anti-cancer effects and underlying mechanisms of marine algae polysaccharides

W Yao, HM Qiu, KL Cheong, S Zhong - International Journal of Biological …, 2022 - Elsevier
Cancer is a leading cause of death in both developing and developed countries. With the
increase in the average global life expectancy, it has become a major health problem and …

Multifunctional role of fucoidan, sulfated polysaccharides in human health and disease: A journey under the sea in pursuit of potent therapeutic agents

B Pradhan, S Patra, R Nayak, C Behera… - International Journal of …, 2020 - Elsevier
Fucoidan is a complex polysaccharide (molecular weight 10,000–100,000 Da) derived from
brown algae which comprises of L-fucose and sulfate groups have potential as therapeutic …

A review about the development of fucoidan in antitumor activity: Progress and challenges

L Wu, J Sun, X Su, Q Yu, Q Yu, P Zhang - Carbohydrate polymers, 2016 - Elsevier
Fucoidan is composed of l-fucose, sulfate groups and one or more small proportions of d-
xylose, d-mannose, d-galactose, l-rhamnose, arabinose, glucose, d-glucuronic acid and …

[HTML][HTML] Clinical applications of fucoidan in translational medicine for adjuvant cancer therapy

HY Hsu, PA Hwang - Clinical and Translational Medicine, 2019 - Springer
The chemical composition of fucoidan, a kind of sulfated polysaccharide mainly derived from
brown seaweed, includes a substantial percentage of l-fucose. Fucoidan has various …

A comprehensive review on the health benefits and nutritional significance of fucoidan polysaccharide derived from brown seaweeds in human, animals and aquatic …

M Saeed, MA Arain, S Ali Fazlani… - Aquaculture …, 2021 - Wiley Online Library
Fucoidan is a sulphated polysaccharide isolated from brown seaweeds. It has attracted a lot
of attention due to its multiple physiological and biological properties. The most dominant …

A review on fucoidan antitumor strategies: From a biological active agent to a structural component of fucoidan-based systems

C Oliveira, NM Neves, RL Reis, A Martins… - Carbohydrate Polymers, 2020 - Elsevier
Due to the severe side-effects and the toxicity to healthy tissues, cancer treatments based in
chemotherapy have not fully achieved the desire outcomes so far. The use of natural …

Impacts of oxidative stress and PI3K/AKT/mTOR on metabolism and the future direction of investigating fucoidan-modulated metabolism

JP Shiau, YT Chuang, YB Cheng, JY Tang, MF Hou… - Antioxidants, 2022 - mdpi.com
The critical factors for regulating cancer metabolism are oxidative stress and
phosphoinositide-3-kinase/AKT serine-threonine kinase/mechanistic target of the rapamycin …

Fucoidan, a natural biopolymer in cancer combating: From edible algae to nanocarrier tailoring

SM Etman, YSR Elnaggar, OY Abdallah - International journal of biological …, 2020 - Elsevier
Fucoidan is an edible algae that has long been used as part of east Asians' diet. Recently,
various pharmacological activities of the polymer have been discovered including its ability …

In vitro anticancer activity of fucoidan extracted from Sargassum cinereum against Caco-2 cells

SS Narayani, S Saravanan, J Ravindran… - International journal of …, 2019 - Elsevier
Fucoidan is a marine sulfated polysaccharide, which is extracted from brown seaweed that
has a wide range of bioactivities including anti-cancer properties. However, the underlying …

Fucoidan structure and its impact on glucose metabolism: Implications for diabetes and cancer therapy

B Mabate, CD Daub, S Malgas, AL Edkins, BI Pletschke - Marine drugs, 2021 - mdpi.com
Fucoidans are complex polysaccharides derived from brown seaweeds which consist of
considerable proportions of L-fucose and other monosaccharides, and sulphated ester …