Exploring uncatalogued genetic variation in antimicrobial resistance gene families in Escherichia coli: an observational analysis

S Lipworth, D Crook, AS Walker, T Peto… - The Lancet …, 2024 - thelancet.com
Background Antimicrobial resistance (AMR) in Escherichia coli is a global problem
associated with substantial morbidity and mortality. AMR-associated genes are typically …

The Dissemination of Multidrug-Resistant and Hypervirulent Klebsiella pneumoniae Clones Across the Kingdom of Saudi Arabia

J Huang, AY Alhejaili, UH Alkherd… - Emerging Microbes & …, 2024 - Taylor & Francis
Klebsiella pneumoniae is a Gram-negative bacterium associated with a wide range of
community-and hospital-acquired infections. The emergence of clonal hypervirulent strains …

The spread of antibiotic resistance is driven by plasmids amongst the fastest evolving and of broadest host range

C Coluzzi, EPC Rocha - bioRxiv, 2024 - biorxiv.org
Microorganisms endure novel challenges for which other microorganisms in other biomes
may have already evolved solutions. This is the case of nosocomial bacteria under antibiotic …

Plasmid-driven strategies for clone success in Escherichia coli

S Arredondo-Alonso, AK Pöntinen, JA Gama… - bioRxiv, 2023 - biorxiv.org
Escherichia coli is a major human pathogen and the most widely studied microbe in history,
but its extrachromosomal elements known as plasmids remain poorly delineated. Here we …

Ganzgenomsequenzierung in der Hygiene–sinnvoller Einsatz: Chancen und Grenzen

F Maechler - Krankenhaushygiene up2date, 2024 - thieme-connect.com
Hygieneteams werden im Krankenhaus oft mit der Frage konfrontiert, ob es sich bei
Erregern mit pathogenem Potenzial oder auffälligem Resistenzmuster, die in zeitlichem und …