Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission

C Eccleston, E Fisher, RF Howard, R Slater… - The Lancet Child & …, 2021 - thelancet.com
Executive summary Every infant, child, and adolescent will experience pain at times
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …

Neuropathic pain in children: steps towards improved recognition and management

SM Walker - EBioMedicine, 2020 - thelancet.com
Neuropathic pain in children can be severe and persistent, difficult to recognise and
manage, and associated with significant pain-related disability. Recognition based on …

[HTML][HTML] Cisplatin induced alterations in nociceptor developmental trajectory elicits a TrkA dependent platinum-based chemotherapy induced neuropathic pain

L Hardowar, T Valentine, MDV Lobo, J Corbett, B Owen… - Neuroscience, 2024 - Elsevier
Cisplatin-based chemotherapy is a common treatment for paediatric cancer. Unfortunately,
cisplatin treatment causes neuropathic pain, a highly prevalent adverse health related …

A bibliometric analysis of chemotherapy and pain in pediatric patients over the last decade

H Huang, G Cai, H Xiang - Frontiers in Pediatrics, 2023 - frontiersin.org
Background Chemotherapy is an important treatment for children with cancer, and
chemotherapy-induced pain is an important role in affecting patients' quality of life. In our …

Early-life cisplatin exposure induces neuroinflammation and chemotherapy-induced neuropathic pain

M Da Vitoria Lobo, L Hardowar… - Disease Models & …, 2024 - journals.biologists.com
Chemotherapy-induced neuropathic pain (CINP) is a common adverse health-related
comorbidity that manifests later in life in patients with paediatric cancer. Current analgesia is …

Combined effect of Neurotropin® and methylcobalamin on postherpetic neuralgia in mice infected with herpes simplex virus type-1

T Andoh, T Kikukawa, A Kotani, Y Kurokawa… - Journal of …, 2024 - Elsevier
Background Postherpetic pain (PHP) is difficult to control. Although Neurotropin®(NTP) and
methylcobalamin (MCB) are often prescribed to treat the pain, the efficacy of combined …

The Role of Vascular-Immune Interactions in Modulating Chemotherapy Induced Neuropathic Pain

T Valentine, L Hardowar, J Elphick-Ross… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy causes sensory disturbances in cancer patients that results in neuropathies
and pain. As cancer survivorships has dramatically increased over the past 10 years, pain …

Chronic pain and childhood cancer survivorship

R Grundy, RP Hulse - Current Opinion in Physiology, 2019 - Elsevier
Research advances have led to an increased survival for childhood cancer and importantly,
recognition of the quality of that survivorship. Unfortunately, adult survivors of childhood …

Neuroinflammation induces nerve growth factor dependent nociceptor sensitisation in a neonatal rodent model of platinum-based chemotherapy induced neuropathic …

M Da Vitoria Lobo, L Hardowar, T Valentine, L Tomblin… - bioRxiv, 2023 - biorxiv.org
Chemotherapy-induced peripheral sensory neuropathy (CIPN) is a highly prevalent adverse
health related comorbidity that manifests later in life in adult patients who have undergone …

Neural circuits of chronic pain

R Kuner, H Flor - Neuroscience, 2018 - ibroneuroscience.org
Pain subserves key protective functions in living organisms. Not surprisingly, Charles
Darwin described pain to be 'a homeostatic emotion', much like hunger and thirst, which he …