The epithelial tissues that line our body, such as the skin and gut, have remarkable
regenerative prowess and continually renew throughout our lifetimes. Owing to their barrier …

The environmental and occupational risk we confront from agricultural chemicals increases
as their presence in natural habitats rises to hazardous levels, building a major part of the …

In inflammatory bowel disease (IBD), chronic inflammation in the gastrointestinal tract can
lead to tissue damage and remodelling, which can ultimately result in fibrosis. Prolonged …

Innate immune cells play essential roles in modulating both immune defense and
inflammation by expressing a diverse array of cytokines and inflammatory mediators …

Eosinophilic esophagitis (EoE) and inflammatory bowel disease (IBD) are chronic
inflammatory disorders of the gastrointestinal tract, with EoE predominantly provoked by …

Cross talk between immune cells and the intestinal crypt is critical in maintaining intestinal
homeostasis. Recent studies highlight the direct impact of vitamin D receptor (VDR) …

Chronic rhinosinusitis (CRS) is a common inflammatory disease of the sinonasal cavity that
affects millions of individuals worldwide. The complex pathophysiology of CRS remains …

The stress-induced keratin intermediate filament gene/protein KRT16 (K16) is spatially
restricted to the suprabasal compartment of the epidermis and extensively used as a …

The intestinal epithelium fulfills important physiological functions and forms a physical
barrier to the intestinal lumen. Barrier function is regulated by several pathways, and its …

Severe skin and soft-tissue infections can lead to septic shock and organ failure. Antibiotic
treatment is turning ineffective due to the rise of antimicrobial resistance. This calls for the …