Angiogenesis plays an important role not only in the growth and regeneration of tissues in
humans but also in pathological conditions such as inflammation, degenerative disease and …

Background Induced pluripotent stem-cell derived endothelial cells (iPSC-ECs) can be
generated from any somatic cell and their iPSC sources possess unlimited self-renewal …

Cardiovascular disease is an inflammatory disorder that may benefit from appropriate
modulation of inflammation. Systemic treatments lower cardiac events but have serious …

While encapsulation of cells within protective nanoporous gel cocoons increases cell
retention and pro-survival integrin signaling, the influence of cocoon size and intra-capsular …

Medical devices are a mainstay of the healthcare industry, providing clinicians with
innovative tools to diagnose, monitor, and treat a range of medical conditions. For …

Despite being one of the most clinically trialed cell therapies, bone marrow‐mononuclear
cell (BM‐MNC) infusion has largely failed to fulfill its clinical promise. Implanting biomimetic …

The combination of bone marrow mesenchymal stem cell (BMSC) sheets and titanium
implants (BMSC sheet–implant complexes) can accelerate osseointegration. However …

Encapsulation devices are an emerging barrier technology designed to prevent the
immunorejection of replacement cells in regenerative therapies for intractable diseases …

The functionality and durability of implanted biomaterials are often compromised by an
exaggerated foreign body reaction (FBR). M1/M2 polarization of macrophages is a critical …

Design of bioinspired materials that mimic the extracellular matrix (ECM) at the nanoscale is
a challenge in tissue engineering. While nanofibrillar gelatin materials mimic chemical …